Evidence map›Paper›PMID 22556171›Full record

ArticleJournal of Zhejiang University. Science. B2012

Association between TaqIB polymorphism of cholesteryl ester transfer protein and coronary artery disease in the Chinese population.

Qi Yu, En-qi Liu, Si-hai Zhao, Ya-feng Li, Yan-li Wang, Yu-long Chen, Ke-na Wei, Bing-qiao Huang, Jian-lin Fan, Peng-hui Yang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Estrogen receptor alpha polymorphisms, estradiol level, and occurrence of atherosclerosis risk factors in healthy postmenopausal women.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Qi YuResearch Institute of Atherosclerotic Disease, Xi'an Jiaotong University School of Medicine, Shaanxi, China.
En-qi Liu
Si-hai Zhao
Ya-feng Li
Yan-li Wang
Yu-long Chen
Ke-na Wei
Bing-qiao Huang
Jian-lin Fan
Peng-hui Yang
Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess whether the TaqIB polymorphism of cholesteryl ester transfer protein (CETP) is associated with coronary artery disease (CAD) in Chinese population, we performed a meta-analysis in this paper.

methodsWe searched PubMed, Embase, the Science Citation Index (SCI), the China Biological Medicine database (CBM), the China National Knowledge Infrastructure (CNKI), and the Wanfang database for relevant articles. Data were extracted, and pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.

resultsThe literature search yielded 448 studies, in which 10 case-control studies including 1694 cases and 1456 controls matched the selection criteria. The combined B1 and B2 allele frequencies were 0.587 and 0.413, respectively. The pooled OR was 1.10 (95% CI, 0.89-1.34) for comparing the B1B1 or B1B2 carriers with B2B2 carriers, and was 1.27 (95% CI, 1.09-1.49) in the B1B1 carriers versus B2B2 or B1B2 carriers.

conclusionsIn the present study, the TaqIB polymorphism of CETP was found to be associated with CAD in the Chinese population.

Indexed as

HeterozygoteAdultAgedAged, 80 and overChinaCholesterol Ester Transfer ProteinsCoronary Artery DiseaseFemaleGenetic Association StudiesGenetic Predisposition to DiseaseHumansMaleMiddle AgedPolymorphism, Single NucleotidePrevalenceRisk AssessmentCholesterol Ester Transfer Proteins

Identifiers

PMID22556171
PMCPMC3348224
OpenAlexW1999716162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.