Evidence map›Paper›PMID 22556059›Full record

ArticleArthritis care & research2012

Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis.

Adam P Goode, Stephen W Marshall, Jordan B Renner, Timothy S Carey, Virginia B Kraus, Debra E Irwin, Til Stürmer, Joanne M Jordan

Abstract read
In one paragraph

Article in Arthritis care & research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 78 citations in OpenAlex.

  1. Trial
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  10. Sex Difference in OA: Should We Blame Estrogen?European journal of rheumatology · 2023
    Article
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  19. Associated factors for and progression rate of sacroiliac joint degeneration in subjects undergoing comprehensive medical checkups.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020
    Article
  20. Protective Effect of Alendronate on Lumbar Facet Degeneration in Ovariectomized Rats.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Adam P GoodeDuke University, Durham, NC 27708, USA. adam.goode@duke.edu
Stephen W Marshall
Jordan B Renner
Timothy S Carey
Virginia B Kraus
Debra E Irwin
Til Stürmer
Joanne M Jordan
University of North Carolina at Chapel Hill · USDuke University · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI CATHLEEN S COLON-EMERIC · 2006 to 2026
$24.6M
Thermally-Triggered Intra-articular Drug Delivery for OAP01AR050245 · NIAMS · DUKE UNIVERSITY · PI GUILAK, FARSHID · 2003 to 2012
$11.5M
Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
Duke Mentored CER Scholar ProgramK12HS019479 · AHRQ · DUKE UNIVERSITY · PI ODDONE, EUGENE Z. · 2010 to 2010
$1.9M
Women's knee motion patterns in functional activitiesP60AR030701 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI LEE, GRETA M · 1986 to 2001
$1.9M
AHRQ HHS HS19479-01NIAMS NIH HHS 1-L30-AR057661-02NIAMS NIH HHS 5P01-AR-050245NIAMS NIH HHS 5-P60-AR30701NIAMS NIH HHS 5-P60-AR49465-03NIAMS NIH HHS L30 AR057661NIAMS NIH HHS P01 AR050245NIAMS NIH HHS P60 AR030701NIAMS NIH HHS P60 AR049465NIA NIH HHS 5P30-AG-028716NIA NIH HHS P30 AG028716NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

objectiveTo determine the prevalence of lumbar spine individual radiographic features (IRFs) of disc space narrowing (DSN), osteophytes (OST), and facet joint osteoarthritis (FOA); to describe the frequencies of demographic, clinical, and radiographic knee, hip, and hand osteoarthritis (OA) across lumbar spine IRFs; and to determine factors associated with lumbar spine IRFs.

methodsWe conducted a cross-sectional study of 840 participants enrolled in the Johnston County Osteoarthritis Project (2003-2004). Sample-based prevalence estimates were generated for each lumbar spine IRF. The associations between lumbar spine IRFs and demographic, clinical, and peripheral joint OA were determined with logistic regression models.

resultsSample-based prevalence estimates were similar for DSN (57.6%) and FOA (57.9%) but higher for OST (88.1%), with significant differences across race and sex. Hand and knee OA frequencies increased across IRFs, whereas the effect was absent for hip OA. African Americans had lower odds of FOA (adjusted odds ratio [OR(adj) ] 0.45 [95% confidence interval (95% CI) 0.32-0.62]), while there was no racial association with DSN and OST. Low back symptoms were associated with DSN (OR(adj) 1.37 [95% CI 1.04-1.80]) but not OST or FOA. Knee OA was associated with OST (OR(adj) 1.62 [95% CI 1.16-2.27]) and FOA (OR(adj) 1.69 [95% CI 1.15-2.49]) but not DSN. Hand OA was associated with FOA (OR(adj) 1.67 [95% CI 1.20-2.28]) but not with DSN or OST. No associations were found with hip OA.

conclusionThese findings underscore the importance of analyzing lumbar spine IRFs separately as the associations with demographic, clinical, and radiographic knee, hip, and hand OA differ widely.

Indexed as

AdultAgedAged, 80 and overCross-Sectional StudiesFemaleHand JointsHip JointHumansKnee JointLumbar VertebraeMaleMiddle AgedOsteoarthritisPrevalenceRadiography

Identifiers

PMID22556059
PMCPMC3427717
OpenAlexW1990162424

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.