Evidence map›Paper›PMID 22556050›Full record

Trial reportBMJ (Clinical research ed.)2012

Prevention of acute knee injuries in adolescent female football players: cluster randomised controlled trial.

Markus Waldén, Isam Atroshi, Henrik Magnusson, Philippe Wagner, Martin Hägglund

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ (Clinical research ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00894595 (Preventing Knee Injuries in Adolescent Female Football Players - Protocol of a Cluster-randomized Controlled Trial), which is not on this map. Cited by 180 papers, 37 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 37 pooled it
30.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00894595 nacompletednot on this map

Preventing Knee Injuries in Adolescent Female Football Players - Protocol of a Cluster-randomized Controlled Trial

TypeinterventionalSponsorRegion SkaneRan2008 to 2010Enrolled4,564ConditionsKnee InjuryArmsKnäkontroll, SISU Idrottsböcker©, Sweden, 2005
3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 37 syntheses or guidelines pooled it, 484 citations in OpenAlex.

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  8. Reducing ACL injury risk: A meta-analysis of prevention programme effectiveness.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
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120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Markus WaldénDivision of Community Medicine, Department of Medical and Health Sciences, Linköping University, 581 83 Linköping, Sweden. markus.walden@telia.com
Isam Atroshi
Henrik Magnusson
Philippe Wagner
Martin Hägglund
Linköping University · SELund University · SEHässleholms Sjukhus · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of neuromuscular training in reducing the rate of acute knee injury in adolescent female football players.

designStratified cluster randomised controlled trial with clubs as the unit of randomisation.

setting230 Swedish football clubs (121 in the intervention group, 109 in the control group) were followed for one season (2009, seven months).

participants4564 players aged 12-17 years (2479 in the intervention group, 2085 in the control group) completed the study.

intervention15 minute neuromuscular warm-up programme (targeting core stability, balance, and proper knee alignment) to be carried out twice a week throughout the season.

main outcome measuresThe primary outcome was rate of anterior cruciate ligament injury; secondary outcomes were rates of severe knee injury (>4 weeks' absence) and any acute knee injury.

resultsSeven players (0.28%) in the intervention group, and 14 (0.67%) in the control group had an anterior cruciate ligament injury. By Cox regression analysis according to intention to treat, a 64% reduction in the rate of anterior cruciate ligament injury was seen in the intervention group (rate ratio 0.36, 95% confidence interval 0.15 to 0.85). The absolute rate difference was -0.07 (95% confidence interval -0.13 to 0.001) per 1000 playing hours in favour of the intervention group. No significant rate reductions were seen for secondary outcomes.

conclusionsA neuromuscular warm-up programme significantly reduced the rate of anterior cruciate ligament injury in adolescent female football players. However, the absolute rate difference did not reach statistical significance, possibly owing to the small number of events.

trial registrationClinical trials NCT00894595.

Indexed as

Anterior Cruciate Ligament InjuriesAdolescentAthletic InjuriesChildCluster AnalysisExerciseExercise TherapyFemaleHumansIntention to Treat AnalysisKnee InjuriesOutcome Assessment, Health CareRegression AnalysisSex CharacteristicsSex DistributionSoccer

Identifiers

PMID22556050
PMCPMC3342926
OpenAlexW2128065283

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.