Evidence map›Paper›PMID 22555636›Full record

ArticleCardiovascular journal of Africa2012

Prognostic role of Helicobacter pylori infection in acute coronary syndrome: a prospective cohort study.

R Eskandarian, R Ghorbani, M Shiyasi, B Momeni, K Hajifathalian, M Madani

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Cardiovascular journal of Africa, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05789550 (HELICOBACTER PYLORI INFECTION IN TYPE 2 DIABETES MELLITUS IN ASSIUT UNIVERSITY HOSPITAL), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05789550 unknown statusnot on this mapstarted 2023, after this paper: background citation

Helicobacter pylori infection in type 2 diabetes mellitus in assiut university hospital

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled146ConditionsH Pylori InfectionArmsALL PATIENT DIABETIC IN THIS PERIOD WILL BE INCLUDED IN THE STUDY
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. ShouldAnnals of medicine and surgery (2012) · 2026
    Article
  3. Metabolism open · 2025
    Review
  4. Article
  5. Heliyon · 2023
    Article
  6. Article
  7. Relationship BetweenInternational journal of general medicine · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Association between Bacterial Infection and Peripheral Vascular Disease: A Review.The International journal of angiology : official publication of the International College of Angiology, Inc · 2016
    Review
  14. Review
  15. Helicobacter pylori infection and the risk of acute coronary syndrome: a nationwide retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Article
  16. Clinical significance of Helicobacter pylori infection in patients with acute coronary syndromes: an overview of current evidence.Clinical research in cardiology : official journal of the German Cardiac Society · 2014
    Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

R EskandarianDepartment of Cardiology, Faculty of Medicine, Seman University of Medical Sciences, Semnan, Iran.
R Ghorbani
M Shiyasi
B Momeni
K Hajifathalian
M Madani
Semnan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a prospective cohort study, we evaluated the effect of Helicobacter pylori seropositivity on the risk of future adverse cardiovascular outcomes among patients with acute coronary syndrome (ACS). In 433 patients, IgA and IgG antibodies to H pylori, along with classic risk factors, including hypertension, diabetes, hyperlipidaemia, smoking and family history of coronary artery disease (CAD) were determined. Short and long-term follow-up information on adverse outcomes, defined as recurrence of unstable angina, myocardial infarction, coronary angioplasty, coronary artery bypass graft surgery, and sudden cardiac death was obtained. None of the classic CAD risk factors correlated with incidence of either short- or long-term outcomes. Seropositivity for H pylori was significantly associated with risk of short-term adverse outcomes, and independently predicted their incidence in multivariate regression (R = 3.05, p < 0.001). Results failed to show such an association between H pylori seropositivity and long-term adverse outcomes. H pylori infection may affect short-term prognosis in patients with ACS. Randomised trials are needed to evaluate the role of H pylori eradication in these patients.

Indexed as

Acute Coronary SyndromeAdultAgedAged, 80 and overAntibodies, BacterialCohort StudiesFemaleHelicobacter InfectionsHelicobacter pyloriHumansImmunoglobulin AImmunoglobulin GMaleMiddle AgedPrevalencePrognosisAntibodies, BacterialImmunoglobulin AImmunoglobulin G

Identifiers

PMID22555636
PMCPMC3721895
OpenAlexW1984092732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.