ArticleAJNR. American journal of neuroradiology2012
Carotid artery plaque classification: does contrast enhancement play a significant role?
Article in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology.AJNR. American journal of neuroradiology · 2018Guideline
- Correlation between fissured fibrous cap and contrast enhancement: preliminary results with the use of CTA and histologic validation.AJNR. American journal of neuroradiology · 2014Trial
- Diagnostic value of cervical vascular ultrasound combined with CT angiography in carotid artery plaque in patients with cerebral infarction.Malawi medical journal : the journal of Medical Association of Malawi · 2026Article
- Identification of vulnerable carotid plaque with histologically validated CT-derived plaque maps.The British journal of radiology · 2023Article
- CT Attenuation Analysis of Carotid Intraplaque Hemorrhage.AJNR. American journal of neuroradiology · 2018Article
- Production of IL-8, VEGF and Elastase by Circulating and Intraplaque Neutrophils in Patients with Carotid Atherosclerosis.PloS one · 2015Article
- Reproducibility of two different methods for performing mean gray value evaluation of cyst content in endometriomas using VOCAL.Journal of medical ultrasonics (2001) · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposePrevious articles have demonstrated that carotid artery plaques may have enhancement after administration of contrast material. The purpose of this study was to evaluate the effect of enhancement in carotid artery classification. MATERIALS AND
methodsThree hundred eighty consecutive patients (235 men, 145 women; median age 64, age range 32-87 years) were analyzed using a multidetector row CT scanner. Examinations were performed before and after CM administration. Carotid artery plaques with a attenuation value <60 HU were considered fatty, those from 60-130 HU were considered mixed, and those >130 HU were considered calcified. χ(2) tests, Student t tests, and Cohen analyses were performed.
resultsBefore CM administration, we observed 226 calcified, 175 mixed, and 206 fatty plaques; after CM administration, 229 calcified, 213 mixed, and 165 fatty plaques were observed. A statistically significant difference between these 2 groups was observed (P = .016). We found that 19.9% of fatty plaques become mixed (n = 41), whereas 1.7% of the mixed plaques become calcified (n = 3). All calcified plaques remained in the same category. Fatty plaques that changed type showed a larger enhancement compared with those that remained in the same class (P = .001). Cohen analyses showed very good agreement between observers before (κ = 0.834) and after contrast material administration (κ = 0.86).
conclusionsThe results of this study indicate that the carotid artery plaques (fatty and mixed) significantly change according to whether analysis is performed before or after administration of contrast material.
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