Evidence map›Paper›PMID 22555463›Full record

ReviewGut microbes

Infection strategies of enteric pathogenic Escherichia coli.

Abigail Clements, Joanna C Young, Nicholas Constantinou, Gad Frankel

Open access · bronzeAbstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 347 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. EnteroaggregativeEcoSal Plus · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. First recorded food-borne outbreak of gastroenteritis caused by enteroinvasive Escherichia coli serotype O8:H19 in Thailand.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Genomic Dissection of an EnteroaggregativeInternational journal of molecular sciences · 2024
    Article
  16. Article
  17. Review
  18. Comparative prevalence of diarrheagenicThe Pan African medical journal · 2024
    Article
  19. Article
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Abigail ClementsCentre for Molecular Microbiology and Infection, Imperial College, London, UK. a.clements@imperial.ac.uk
Joanna C Young
Nicholas Constantinou
Gad Frankel
Imperial Valley College · USImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteric Escherichia coli (E. coli) are both natural flora of humans and important pathogens causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been divided into 6 pathotypes, with further pathotypes often proposed. In this review we suggest expansion of the enteric E. coli into 8 pathotypes to include the emerging pathotypes of adherent invasive E. coli (AIEC) and Shiga-toxin producing enteroaggregative E. coli (STEAEC). The molecular mechanisms that allow enteric E. coli to colonize and cause disease in the human host are examined and for two of the pathotypes that express a type 3 secretion system (T3SS) we discuss the complex interplay between translocated effectors and manipulation of host cell signaling pathways that occurs during infection.

Indexed as

DiarrheaEscherichia coliEscherichia coli InfectionsHumansVirulenceVirulence FactorsVirulence Factors

Identifiers

PMID22555463
PMCPMC3370951
OpenAlexW2069741608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.