Evidence map›Paper›PMID 22555003›Full record

ArticleTheoretical population biology2012

Ascertainment correction for a population tree via a pruning algorithm for likelihood computation.

Arindam RoyChoudhury, Elizabeth A Thompson

Abstract read
In one paragraph

Article in Theoretical population biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The Probability of Joint Monophyly of Samples of Gene Lineages for All Species in an Arbitrary Species Tree.Journal of computational biology : a journal of computational molecular cell biology · 2022
    Article
  2. Article
  3. The probability of monophyly of a sample of gene lineages on a species tree.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arindam RoyChoudhuryDepartment of Biostatistics, Columbia University, New York, NY 10032, USA. ar2946@columbia.edu
Elizabeth A Thompson

Funding

Statistical Methods for X-Chromosome Genetic DataP01GM099568 · NIGMS · UNIVERSITY OF WASHINGTON · PI WEIR, BRUCE S. · 2012 to 2016
$7.3M
THEORETICAL QUANTITATIVE GENETICSP01GM045344 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI MACKAY, TRUDY F · 1991 to 2005
$7.2M
Phylogeny and Genomic Inference for Quantitative TraitsR01GM071639 · NIGMS · UNIVERSITY OF WASHINGTON · PI FELSENSTEIN, JOSEPH · 2005 to 2008
$909k
GENE EXPRESSION DURING THE MAMMALIAN CELL CYCLER01GM032544 · NIGMS · ROCKEFELLER UNIVERSITY · PI HEINTZ, NATHANIEL · 1985 to 1995
–
NIGMS NIH HHS GM 32544-14S1NIGMS NIH HHS GM-45344NIGMS NIH HHS P01 GM045344NIGMS NIH HHS P01 GM099568NIGMS NIH HHS R01 GM071639NIGMS NIH HHS R01 GM071639-01A1
6 · The paper itself

Abstract

We present a method for correcting ascertainment-bias in a coalescent-based likelihood for population trees. Our method is computationally simple and fast. To correct for the bias we compute the probability of allele-counts conditioned on the locus being included. This conditional probability is simply the uncorrected likelihood divided by the inclusion probability. A modification of a pruning algorithm is introduced so that the inclusion probability can be computed with a single run of the algorithm. Our computation is exact and avoids Monte-Carlo based methods.

Indexed as

AlgorithmsGenetics, PopulationLikelihood FunctionsPolymorphism, Single Nucleotide

Identifiers

PMID22555003
PMCPMC4181591

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.