ArticleMolecular imaging2012
Small-animal imaging using clinical positron emission tomography/computed tomography and super-resolution.
Article in Molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Feasibility of in vivo small animal imaging using a clinical total-body PET/CT system.EJNMMI physics · 2025Article
- PET imaging and quantification of small animals using a clinical SiPM-based camera.EJNMMI physics · 2023Article
- Development of a Neurotensin-DerivedCancers · 2022Article
- Effects of administration route on uptake kinetics ofScientific reports · 2021Article
- Small animal PET: a review of what we have done and where we are going.Physics in medicine and biology · 2020Review
- Morphology of the Vasculature and Blood Supply of the Brown Adipose Tissue Examined in an Animal Model by Micro-CT.BioMed research international · 2020Article
- Development and Characterization of a Genetic Mouse Model of KRAS Mutated Colorectal Cancer.International journal of molecular sciences · 2019Article
- Application ofOncotarget · 2017Article
- High-resolution dynamic imaging and quantitative analysis of lung cancer xenografts in nude mice using clinical PET/CT.Oncotarget · 2017Article
- Article
- NEMA NU 4-Optimized Reconstructions for Therapy Assessment in Cancer Research with the Inveon Small Animal PET/CT System.Molecular imaging and biology · 2015Article
- Tumor quantification in clinical positron emission tomography.Theranostics · 2013Review
- The motivations and methodology for high-throughput PET imaging of small animals in cancer research.European journal of nuclear medicine and molecular imaging · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Considering the high cost of dedicated small-animal positron emission tomography/computed tomography (PET/CT), an acceptable alternative in many situations might be clinical PET/CT. However, spatial resolution and image quality are of concern. The utility of clinical PET/CT for small-animal research and image quality improvements from super-resolution (spatial subsampling) were investigated. National Electrical Manufacturers Association (NEMA) NU 4 phantom and mouse data were acquired with a clinical PET/CT scanner, as both conventional static and stepped scans. Static scans were reconstructed with and without point spread function (PSF) modeling. Stepped images were postprocessed with iterative deconvolution to produce super-resolution images. Image quality was markedly improved using the super-resolution technique, avoiding certain artifacts produced by PSF modeling. The 2 mm rod of the NU 4 phantom was visualized with high contrast, and the major structures of the mouse were well resolved. Although not a perfect substitute for a state-of-the-art small-animal PET/CT scanner, a clinical PET/CT scanner with super-resolution produces acceptable small-animal image quality for many preclinical research studies.
Indexed as
Identifiers
22554485PMC3694434What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.