Evidence map›Paper›PMID 22554179›Full record

ReviewWomen's health (London, England)2012

The role of vitamin D in pregnancy and lactation: emerging concepts.

Carol L Wagner, Sarah N Taylor, Donna D Johnson, Bruce W Hollis

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Women's health (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03051867 (Vitamin D Status and Metabolism in Pregnant and Nonpregnant Control Women Consuming Controlled and Equivalent Intakes of Vitamin D), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03051867 completednot on this map

Vitamin D Status and Metabolism in Pregnant and Nonpregnant Control Women Consuming Controlled and Equivalent Intakes of Vitamin D

TypeobservationalSponsorCornell UniversityRan2009 to 2011Enrolled47ConditionsPregnancy
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.

  1. Maternal Dietary Factors and the Risk of Autism Spectrum Disorders: A Systematic Review of Existing Evidence.Autism research : official journal of the International Society for Autism Research · 2020
    Pooled it
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  19. Evaluating Vitamin D Status in Infants Less than Seven Months; What Are the Preferred Biochemical Measurements?Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carol L WagnerDivision of Neonatology, Medical University of South Carolina, Charleston, SC, USA. wagnercl@musc.edu
Sarah N Taylor
Donna D Johnson
Bruce W Hollis
Medical University of South Carolina · US

Funding

Establishing the Vitamin D Requirements During LactationR01HD047511 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOLLIS, BRUCE W · 2006 to 2010
$2.8M
Evaluation of Vitamin D Requirements During PregnancyR01HD043921 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOLLIS, BRUCE W · 2003 to 2007
$2.6M
NICHD NIH HHS R01 HD043921NICHD NIH HHS R01 HD047511NICHD NIH HHS R01 HD47511
6 · The paper itself

Abstract

Pregnancy is a critical time in the lifecycle of a woman where she is responsible not only for her own well-being, but also that of her developing fetus, a process that continues during lactation. Until recently, the impact of vitamin D status during this period had not been fully appreciated. Data regarding the importance of vitamin D in health have emerged to challenge traditional dogma, and suggest that vitamin D - through its effect on immune function and surveillance - plays a role beyond calcium and bone metabolism on the health status of both the mother and her fetus. Following birth, this process persists; the lactating mother continues to be the main source of vitamin D for her infant. Thus, during both pregnancy and lactation, maternal deficiency predicts fetal and infant deficiency; the significance of this is just beginning to be understood and will be highlighted in this review.

Indexed as

FemaleHumansLactationMaternal Nutritional Physiological PhenomenaMilk, HumanPregnancyPregnancy ComplicationsVitamin DVitamin D-Binding ProteinVitamin D DeficiencyVitaminsVitamin DVitamin D-Binding ProteinVitamins

Identifiers

PMID22554179
PMCPMC4365424
OpenAlexW2133124188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.