Evidence map›Paper›PMID 22553310›Full record

ArticleJournal of feline medicine and surgery2012

Markers of Borna disease virus infection in cats with staggering disease.

Jonas J Wensman, Karin H Jäderlund, Malin H Gustavsson, Helene Hansson-Hamlin, Erika Karlstam, Inger Lilliehöök, Inga-Lena Ö Oström, Sándor Belák, Mikael Berg, Bodil S Holst

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Negative-Strand RNA Virus-Vectored Vaccines.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
  5. Article
  6. Bornaviruses in naturally infectedInfection ecology & epidemiology · 2019
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Jonas J WensmanDepartment of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden. Jonas.Wensman@slu.se
Karin H Jäderlund
Malin H Gustavsson
Helene Hansson-Hamlin
Erika Karlstam
Inger Lilliehöök
Inga-Lena Ö Oström
Sándor Belák
Mikael Berg
Bodil S Holst
Swedish University of Agricultural Sciences · SESwedish Veterinary Agency · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Borna disease virus (BDV) is a RNA-virus causing neurological disorders in a wide range of mammals. In cats, BDV infection may cause staggering disease. Presently, staggering disease is a tentative clinical diagnosis, only confirmed at necropsy. In this study, cats with staggering disease were investigated to study markers of BDV infection aiming for improvement of current diagnostics. Nineteen cats fulfilled the inclusion criteria based on neurological signs and pathological findings. In 17/19 cats, BDV infection markers (BDV-specific antibodies and/or BDV-RNA) were found, and antibodies in serum (13/16, 81%) were the most common marker. BDV-RNA was found in 11/19 cats (58%). In a reference population without neurological signs, 4/25 cats were seropositive (16%). The clinical history and neurological signs in combination with presence of BDV infection markers, where serology and rRT-PCR on blood can be helpful tools, improve the diagnostic accuracy in the living cat.

Indexed as

AnimalsAntibodies, ViralAtaxiaBiomarkersBorna DiseaseBorna disease virusCat DiseasesCatsFemaleMaleParesisAntibodies, ViralBiomarkers

Identifiers

PMID22553310
PMCPMC11104187
OpenAlexW2103320107

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.