ArticleProceedings. Biological sciences2012
Genetic diversity at neutral and adaptive loci determines individual fitness in a long-lived territorial bird.
Article in Proceedings. Biological sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Sex-Dependent Influence of Major Histocompatibility Complex Diversity on Fitness in a Social Mammal.Molecular ecology · 2025Article
- Genetic Rescue of the Dinaric Lynx Population: Insights for Conservation From Genetic Monitoring and Individual-Based Modelling.Evolutionary applications · 2025Article
- Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird.Scientific reports · 2024Article
- Article
- Insularity determines nestling sex ratio variation in Egyptian vulture populations.Ecology and evolution · 2023Article
- High MHC diversity confers no advantage for phenotypic quality and reproductive performance in a wild bird.The Journal of animal ecology · 2022Article
- Persistent panmixia despite extreme habitat loss and population decline in the threatened tricolored blackbird (Evolutionary applications · 2021Article
- Article
- Vultures and Livestock: The Where, When, and Why of Visits to Farms.Animals : an open access journal from MDPI · 2020Article
- Genetic drift and bottleneck do not influence diversity in Toll-like receptor genes at a small spatial scale in a Himalayan passerine.Ecology and evolution · 2020Article
- Sea lice loads correlate with the diversity at the Major Histocompatibility Complex -related loci in farmed Atlantic salmon, Salmo salar.Journal of fish diseases · 2019Article
- Landscape homogenization due to agricultural intensification disrupts the relationship between reproductive success and main prey abundance in an avian predator.Frontiers in zoology · 2019Article
- Major histocompatibility complex genes partly explain early survival in house sparrows.Scientific reports · 2017Article
- Estimating genomic diversity and population differentiation - an empirical comparison of microsatellite and SNP variation in Arabidopsis halleri.BMC genomics · 2017Article
- Adult survival selection in relation to multilocus heterozygosity and body size in a tropical bird species, the Zenaida dove, Zenaida aurita.Oecologia · 2016Article
- Local effects drive heterozygosity-fitness correlations in an outcrossing long-lived tree.Proceedings. Biological sciences · 2015Article
- Age-dependent survival of island vs. mainland populations of two avian scavengers: delving into migration costs.Oecologia · 2015Article
- Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
There is compelling evidence about the manifest effects of inbreeding depression on individual fitness and populations' risk of extinction. The majority of studies addressing inbreeding depression on wild populations are generally based on indirect measures of inbreeding using neutral markers. However, the study of functional loci, such as genes of the major histocompatibility complex (MHC), is highly recommended. MHC genes constitute an essential component of the immune system of individuals, which is directly related to individual fitness and survival. In this study, we analyse heterozygosity fitness correlations of neutral and adaptive genetic variation (22 microsatellite loci and two loci of the MHC class II, respectively) with the age of recruitment and breeding success of a decimated and geographically isolated population of a long-lived territorial vulture. Our results indicate a negative correlation between neutral genetic diversity and age of recruitment, suggesting that inbreeding may be delaying reproduction. We also found a positive correlation between functional (MHC) genetic diversity and breeding success, together with a specific positive effect of the most frequent pair of cosegregating MHC alleles in the population. Globally, our findings demonstrate that genetic depauperation in small populations has a negative impact on the individual fitness, thus increasing the populations' extinction risk.
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