Evidence map›Paper›PMID 22552109›Full record

ArticleThe Journal of allergy and clinical immunology2012

Effect of secondhand smoke on asthma control among black and Latino children.

Sam S Oh, Haig Tcheurekdjian, Lindsey A Roth, Elizabeth A Nguyen, Saunak Sen, Joshua M Galanter, Adam Davis, Harold J Farber, Frank D Gilliland, Rajesh Kumar and 14 more

Abstract readMulticenter Study
In one paragraph

Article in The Journal of allergy and clinical immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Context-specific genetic effects inform endotypes and treatment in asthma.The Journal of allergy and clinical immunology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Secondhand Smoking and the Fetus: A Bibliometric Analysis.Medical journal of the Islamic Republic of Iran · 2023
    Article
  8. Unraveling racial disparities in asthma emergency department visits using electronic healthcare records and machine learning.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Exploring the barriers and incentive architecture for modifying smoke exposures among asthmatics.The Journal of asthma : official journal of the Association for the Care of Asthma · 2019
    Article
  14. In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children.Environmental epidemiology (Philadelphia, Pa.) · 2019
    Article
  15. Article
  16. Article
  17. The environment, epigenome, and asthma.The Journal of allergy and clinical immunology · 2017
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 16 institutions in 3 countries.

Sam S OhDepartment of Medicine, University of California, San Francisco, CA 94158-2911, USA. Sam.Oh@ucsf.edu
Haig Tcheurekdjian
Lindsey A Roth
Elizabeth A Nguyen
Saunak Sen
Joshua M Galanter
Adam Davis
Harold J Farber
Frank D Gilliland
Rajesh Kumar
Pedro C Avila
Emerita Brigino-Buenaventura
Rocio Chapela
Jean G Ford
Michael A LeNoir
Fred Lurmann
Kelley Meade
Denise Serebrisky
Shannon Thyne
William Rodriguez-Cintron
Jose R Rodriguez-Santana
L Keoki Williams
Luisa N Borrell
Esteban G Burchard
University of California, San Francisco · USAllergy Associates Research Center · USCentro de Neumologia Pediatrica · PRHenry Ford Health System · USInstituto Nacional de Enfermedades Respiratorias · MXJacobi Medical Center · USJohns Hopkins University · USKaiser Permanente Vallejo Medical Center · USKIPP Bay Area Schools · USLehman College · USNorthwestern Memorial Hospital · USNorthwestern University · USSonoma Technology (United States) · USTexas Children's Hospital · USUniversity of Southern California · USVA Caribbean Healthcare System · PR

Funding

Understanding Asthma EndotypesU19AI077439 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle · 2008 to 2026
$41.1M
ZOLENDRONIC ACID IN CHILDREN W/ SEVERE OSTEOGENESIS IMPERFECTAM01RR000188 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LOUIS, CHRYSTAL U · 1985 to 2011
$30.6M
CLINICAL, PHARMACOLOGY, DRUG ACTION &PHARMACOKINETICST32GM007546 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Radojka Savic · 1985 to 2026
$8.9M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
Postdoctoral training in tobacco controlR25CA113710 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GLANTZ, STANTON ARNOLD · 2006 to 2015
$5.4M
PHARMACOGENOMICS OF INHALED CORTICOSTEROID RESPONSIVENESS IN PATIENTS WITH ASTHMAR01AI079139 · NIAID · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2009 to 2013
$3.9M
Whole Genome Analyses for Asthma in Latino PopulationsR01HL088133 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$3.8M
Mechanism of Endotoxin's Effect On Allergy RiskR01AI061774 · NIAID · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2004 to 2008
$2.9M
VALIDATION OF ADHERENCE DATA--USE IN CLINICAL PRACTICER01DK064695 · NIDDK · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2003 to 2010
$2.7M
Postdoctoral training in tobacco controlT32CA113710 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LING, PAMELA MAY · 2016 to 2020
$2.6M
Case-control Association Studies and Genetic ConfoundingR01HL078885 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2005 to 2009
$1.9M
USING INFORMATION TECHNOLOGY TO IMPROVE ASTHMA ADHERENCER01HL079055 · NHLBI · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2005 to 2008
$1.4M
NCI NIH HHS CA113710NCI NIH HHS R25 CA113710NCI NIH HHS T32 CA113710NCRR NIH HHS M01 RR000188NCRR NIH HHS M01-RR00188NHLBI NIH HHS HL078885NHLBI NIH HHS HL079055NHLBI NIH HHS HL088133NHLBI NIH HHS R01 HL078885NHLBI NIH HHS R01 HL079055NHLBI NIH HHS R01 HL088133NIAID NIH HHS AI061774NIAID NIH HHS AI077439NIAID NIH HHS AI079139NIAID NIH HHS R01 AI061774NIAID NIH HHS R01 AI079139NIAID NIH HHS U19 AI077439NIDDK NIH HHS DK064695NIDDK NIH HHS R01 DK064695NIEHS NIH HHS ES015794NIEHS NIH HHS R01 ES015794NIGMS NIH HHS T32 GM007546
6 · The paper itself

Abstract

backgroundAmong patients with asthma, the clinical effect and relative contribution of maternal smoking during pregnancy (in utero smoking) and current secondhand smoke (SHS) exposure on asthma control is poorly documented, and there is a paucity of research involving minority populations.

objectivesWe sought to examine the association between poor asthma control and in utero smoking and current SHS exposure among Latino and black children with asthma.

methodsWe performed a case-only analysis of 2 multicenter case-control studies conducted from 2008-2010 with similar protocols. We recruited 2481 Latino and black subjects with asthma (ages 8-17 years) from the mainland United States and Puerto Rico. Ordinal logistic regression was used to estimate the effect of in utero smoking and current SHS exposures on National Heart, Lung, and Blood Institute-defined asthma control.

resultsPoor asthma control among children 8 to 17 years of age was independently associated with in utero smoking (odds ratio [OR], 1.5; 95% CI, 1.1-2.0). In utero smoking through the mother was also associated with secondary asthma outcomes, including early-onset asthma (OR, 1.7; 95% CI, 1.1-2.4), daytime symptoms (OR, 1.6; 95% CI, 1.1-2.1), and asthma-related limitation of activities (OR, 1.6; 95% CI, 1.2-2.2).

conclusionsMaternal smoking while in utero is associated with poor asthma control in black and Latino subjects assessed at 8-17 years of age.

Indexed as

Black or African AmericanHispanic or LatinoAdolescentAdultAsthmaCase-Control StudiesChildFemaleHumansMaleMaternal-Fetal ExchangePregnancyTobacco Smoke PollutionUnited StatesYoung AdultTobacco Smoke Pollution

Identifiers

PMID22552109
PMCPMC3367092
OpenAlexW2154681017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.