Evidence map›Paper›PMID 22550612›Full record

ArticlePathology research international2012

Development of Immunopathogenesis Strategies to Treat Behçet's Disease.

Osman Köse

Registry-linked trialAbstract read
In one paragraph

Article in Pathology research international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04105439 (Relation Between Plasma Soluble Urokinase Plasminogen Activator Receptor and Behçet's Disease .), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04105439 unknown statusnot on this mapstarted 2021, after this paper: background citation

Relation Between Plasma Soluble Urokinase Plasminogen Activator Receptor and Behçet's Disease .

TypeobservationalSponsorAssiut UniversityRan2021 to 2021Enrolled90ConditionsBehçet Disease
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Interventions for the management of oral ulcers in Behçet's disease.The Cochrane database of systematic reviews · 2014
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Morbus Behçet - a rare disease in Central Europe.Archives of medical science : AMS · 2015
    Article
  7. Article
  8. Behçet's disease leaves the silk road.Postepy dermatologii i alergologii · 2014
    Article
  9. Review
  10. Article
  11. New approaches in immunotherapy of behçet disease.Advanced pharmaceutical bulletin · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Osman KöseDepartment of Dermatology, School of Medicine, Gülhane Military Medical Academy, Tevfik Saglam Street No. 1, 06018 Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet disease is a chronic relapsing vasculitis with unclear etiology and immunopathogenesis. Antigenic stimuli, antigen presenting cells, T cells, monocyte, and neutrophil and endothelial cells are major parts of the pathology of the disease. Understanding of the new pathogenic mechanisms based on molecular structure of the disease helps us in improving the novel therapeutic modalities. These drugs target specific and nonspecific inhibition of the immun system. These therapies include biologic agents, new topical and systemic immunosuppressants, tolerizing agents, and immunoablation. Novel treatment will be promising to treat the especially recalcitrant cases to conventional therapy. In this paper, new aspect of the immunopathogenesis of Behçet's diseases and novel treatment modalities will be discussed.

Identifiers

PMID22550612
PMCPMC3324914

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.