Evidence map›Paper›PMID 22550505›Full record

ArticleStem cells international2012

Application of stem cells in orthopedics.

Andreas Schmitt, Martijn van Griensven, Andreas B Imhoff, Stefan Buchmann

Registry-linked trialAbstract read
In one paragraph

Article in Stem cells international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06960343 (Long Term Clinical Outcome After Arthroscopic Rotator Cuff Repair Augmentation With Autologous Microfragmented Lipoaspirate Tissue), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06960343 recruitingnot on this mapstarted 2025, after this paper: background citation

Long Term Clinical Outcome After Arthroscopic Rotator Cuff Repair Augmentation With Autologous Microfragmented Lipoaspirate Tissue: a Prospective Randomized Controlled Trialin Question Won by Our Research Group.

TypeobservationalSponsorUniversity of MilanRan2025 to 2026Enrolled52ConditionsArthroscopic Rotator Cuff Repair, Augmentation, Microfragmented Adipose TissueArmsmagnetic resonance imaging (MRI), VAS, SST, ASES, CMS scores, and strength measurements in external rotation and abduction
3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  12. Review
  13. Cell-based approaches for augmentation of tendon repair.Techniques in shoulder & elbow surgery · 2017
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreas SchmittDepartment of Sports Orthopedics, Technical University, 81675 Munich, Germany.
Martijn van Griensven
Andreas B Imhoff
Stefan Buchmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell research plays an important role in orthopedic regenerative medicine today. Current literature provides us with promising results from animal research in the fields of bone, tendon, and cartilage repair. While early clinical results are already published for bone and cartilage repair, the data about tendon repair is limited to animal studies. The success of these techniques remains inconsistent in all three mentioned areas. This may be due to different application techniques varying from simple mesenchymal stem cell injection up to complex tissue engineering. However, the ideal carrier for the stem cells still remains controversial. This paper aims to provide a better understanding of current basic research and clinical data concerning stem cell research in bone, tendon, and cartilage repair. Furthermore, a focus is set on different stem cell application techniques in tendon reconstruction, cartilage repair, and filling of bone defects.

Identifiers

PMID22550505
PMCPMC3328166

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.