Evidence map›Paper›PMID 22550495›Full record

ArticleInternational journal of microbiology2012

When ribonucleases come into play in pathogens: a survey of gram-positive bacteria.

Brian C Jester, Pascale Romby, Efthimia Lioliou

Open access · goldAbstract read
In one paragraph

Article in International journal of microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Membrane Localization of RNase Y Is Important for Global Gene Expression inInternational journal of molecular sciences · 2024
    Article
  3. Small regulatory RNAs are mediators of theJournal of bacteriology · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Initiation of mRNA decay in bacteria.Cellular and molecular life sciences : CMLS · 2014
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Brian C JesterArchitecture et réactivité de l'ARN, UPR 9002 CNRS, IBMC, Université de Strasbourg, 15 rue René Descartes, 67084 Strasbourg, France.
Pascale Romby
Efthimia Lioliou
Centre National de la Recherche Scientifique · FRArchitecture et Réactivité de l'arN · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is widely acknowledged that RNA stability plays critical roles in bacterial adaptation and survival in different environments like those encountered when bacteria infect a host. Bacterial ribonucleases acting alone or in concert with regulatory RNAs or RNA binding proteins are the mediators of the regulatory outcome on RNA stability. We will give a current update of what is known about ribonucleases in the model Gram-positive organism Bacillus subtilis and will describe their established roles in virulence in several Gram-positive pathogenic bacteria that are imposing major health concerns worldwide. Implications on bacterial evolution through stabilization/transfer of genetic material (phage or plasmid DNA) as a result of ribonucleases' functions will be covered. The role of ribonucleases in emergence of antibiotic resistance and new concepts in drug design will additionally be discussed.

Identifiers

PMID22550495
PMCPMC3328962
OpenAlexW2071446139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.