ArticleInternational journal of cell biology2012
The many faces of mitochondrial autophagy: making sense of contrasting observations in recent research.
Article in International journal of cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Mitochondria-Associated Degradation Pathway (MAD) Function beyond the Outer Membrane.Cell reports · 2020Article
- MitoBlue as a tool to analyze the mitochondria-lysosome communication.Scientific reports · 2020Article
- Uncoupled turnover disrupts mitochondrial quality control in diabetic retinopathy.JCI insight · 2019Article
- The Role of Inflammatory Response in Stroke Associated Programmed Cell Death.Current neuropharmacology · 2018Review
- ER fatalities-The role of ER-mitochondrial contact sites in yeast life and death decisions.Mechanisms of ageing and development · 2017Review
- Molecular regulation of autophagy and its implications for metabolic diseases.Current opinion in clinical nutrition and metabolic care · 2014Review
- Review
- Article
- The dynamics of the mitochondrial organelle as a potential therapeutic target.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2013Review
- The intriguing life of autophagosomes.International journal of molecular sciences · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research into the selective autophagic degradation of mitochondria-mitophagy-has intensified in recent years, yielding significant insights into the function, mechanism, and regulation of this process in the eukaryotic cell. However, while some molecular players in budding yeast, such as Atg32p, Uth1p, and Aup1p, have been identified, studies further interrogating the mechanistic and regulatory features of mitophagy have yielded inconsistent and sometimes conflicting results. In this review, we focus on the current understanding of mitophagy mechanism, induction, and regulation in yeast, and suggest that differences in experimental conditions used in the various studies of mitophagy may contribute to the observed discrepancies. Consideration and understanding of these differences may help place the mechanism and regulation of mitophagy in context, and further indicate the intricate role that this essential process plays in the life and death of eukaryotic cells.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.