Evidence map›Paper›PMID 22549374›Full record

ArticleSurgical endoscopy2012

Laparoscopic complete mesocolic excision for right colon cancer.

Michel Adamina, Mark L Manwaring, Ki-Jae Park, Conor P Delaney

3 registry-linked trialsAbstract readCase ReportsVideo-Audio Media
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02625272 phase2unknown statusnot on this mapstarted 2015, after this paper: background citation

A Novel Technique of Hand-assisted Laparoscopic Right Hemicolectomy With Complete Mesocolic Excision and Central Vascular Ligation for Right Colon Cancer: A Randomized Controlled Trial

TypeinterventionalSponsorWest China HospitalRan2015 to 2020Enrolled60ConditionsColon NeoplasmsArmsGroup A
NCT05713903 narecruitingnot on this mapstarted 2023, after this paper: background citation

Comparison of Laparoscopic Versus Open Right Colectomy for Right Colon Cancer, According to the Complete Mesocolic Excision (CME) Principles: a Prospective Randomized Controlled Trial

TypeinterventionalSponsorLarissa University HospitalRan2023 to 2028Enrolled114ConditionsColon CancerArmsLaparoscopic right colectomy, Open right colectomy
NCT06049758 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

D2 Versus D3 Dissection in Laparoscopic Right Hemicolectomy In Right Cancer Colon Patients: A Randomized Controlled Trial

TypeinterventionalSponsorGeneral Committee of Teaching Hospitals and Institutes, EgyptRan2024 to 2030Enrolled80ConditionsBlood Loss, Intensive Care, Anastomotic Leakage, Lymph Node DiseaseArmsLAPAROSCOPIC RIGHT HEMICOLECTOMY procedure (intervention), Enoxaparin 40 Mg/0.4 mL Injectable Solution, Levofloxacin 500mg, LAPAROSCOPIC RIGHT HEMICOLECTOMY procedure (Conventional)
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 113 citations in OpenAlex.

  1. Pooled it
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  3. Laparoscopic Versus Open Surgery for Mid-Low Rectal Cancer: a Systematic Review and Meta-Analysis on Short- and Long-Term Outcomes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
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  12. Transmesocolic approach in laparoscopic complete mesocolic excision for right sided colon cancers.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022
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  19. Laparoscopic Colectomy vs Laparoscopic CME: a Retrospective Study of Two Hospitals with Comparable Laparoscopic Experience.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michel AdaminaDivision of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, OH, USA. michel.adamina@gmail.com
Mark L Manwaring
Ki-Jae Park
Conor P Delaney
University Hospitals Case Medical Center · USEast Carolina University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laparoscopic colectomy for colon cancer has become a standard of care, with a number of publications highlighting its safety, improved postoperative recovery, and excellent oncologic outcomes. Complete mesocolic excision, recently reemphasized, is associated with superior oncologic outcomes, although this has not been discussed for laparoscopic surgery. A laparoscopic approach was performed for right colon cancer using a four-trocar technique. The key steps demonstrated are identification and high division of the ileocolic pedicle, medial-to-lateral mobilization of the ascending colon preserving the posterior mesocolic fascia, identification and high division of the right branch of the middle colic artery, mobilization of the greater omentum and hepatic flexure, completion of lateral mobilization of the ascending colon from the retroperitoneum, and mobilization of the small bowel mesentery up to the duodenum. A prospective series of 52 consecutive patients with right colon cancer underwent laparoscopic complete mesocolic excision with high-vessel ligation. Four of the patients required laparoscopic en bloc extended resections for local invasion. The median operative time was 136 min (interquartile range [IQR], 105-167 min), and the median blood loss was 20 ml (IQR, 10-45 ml). The median hospital stay was 3 days (IQR, 3-5 days). All the patients had an R0 oncologic resection with median margins of 12 cm, and a median of 22 lymph nodes (IQR, 18-29 lymph nodes) was retrieved. The median follow-up period was 38 months (IQR, 23-54 months). Of 14 patients with tumor-positive lymph nodes, 2 experienced distant recurrence. There were no local recurrences, but four patients experienced metastatic disease at a median of 37 months (IQR, 22-46 months). The median overall survival time was 38 months (IQR, 23-54 months). The embedded didactic video demonstrates a straight laparoscopic complete mesocolic excision with high-vessel ligation for a patient who had a right colon cancer. Laparoscopic right complete mesocolic excision is a safe and effective procedure associated with excellent 3-year oncologic outcomes and accelerated postoperative recovery.

Indexed as

AdenocarcinomaAgedAged, 80 and overColonic NeoplasmsFemaleFollow-Up StudiesHumansLaparoscopyLength of StayLymphatic MetastasisMaleMesocolonNeoplasm GradingNeoplasm StagingOperative TimeProspective Studies

Identifiers

PMID22549374
OpenAlexW2023027564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.