ArticleEuropean radiology2012
Contrast-induced nephropathy in patients with renal insufficiency undergoing contrast-enhanced MDCT.
Article in European radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Clinical and experimental nephrology · 2020Guideline
- Pooled it
- Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology.Current cardiology reports · 2025Review
- Association Between IV Contrast Media Exposure and Acute Kidney Injury in Patients Requiring Emergency Admission: A Nationwide Observational Study in Japan.Critical care explorations · 2024Observational
- Patients with Different Stages of Chronic Kidney Disease Undergoing Intravenous Contrast-Enhanced Computed Tomography-The Incidence of Contrast-Associated Acute Kidney Injury.Diagnostics (Basel, Switzerland) · 2022Article
- Contrast associated nephropathy after intravenous administration: what is the magnitude of the problem?Renal failure · 2021Review
- Creatinine level variation in patients subjected to contrast-enhanced tomography: a meta-analysis.Jornal vascular brasileiro · 2021Review
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Japanese journal of radiology · 2020Article
- Uric acid and contrast-induced nephropathy: an updated review and meta-regression analysis.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2018Article
- Prediction of presence of kidney disease in patients undergoing intravenous iodinated contrast enhanced computed tomography: a validation study.European radiology · 2017Article
- Contrast-induced nephropathy in CT: incidence, risk factors and strategies for prevention.European radiology · 2016Review
- Article
- Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence.Systematic reviews · 2014Article
- Prediction of presence of kidney disease in a general patient population undergoing intravenous iodinated contrast enhanced computed tomography.European radiology · 2014Article
- Letter to the Editor re: Are intravenous injections of contrast media really less nephrotoxic than intra-arterial injections?European radiology · 2013Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the safety of contrast-enhanced MDCT in patients with renal impairment.
methodsWe conducted a retrospective review of 938 patients with stable renal insufficiency (eGFR between 15 and 60 ml/min) who underwent contrast-enhanced MDCT. SCr levels were measured at baseline and 48-72 h after contrast medium administration. The incidence of contrast-induced nephropathy (CIN) in the total study population was assessed. As a control group, 1,164 separate patients with renal insufficiency who did not receive contrast medium for CT were also reviewed.
resultsThe overall incidence of CIN in the patient population with renal insufficiency was 6.1 %; the incidence was 4.4 %, 10.5 % and 10.0 % for patients whose eGFR was 45-60, 30-45 and ≤30 ml/min, respectively (P < 0.01). In the control group, 5.8 % of patients showed an increase in the SCr level from the baseline. The increase in the SCr level showed no significant difference between the patients who received CM and those who did not (P = 0.82)
conclusionsThe risk of CIN from contrast-enhanced MDCT in patients with renal insufficiency appeared to be low, and there was no significant difference in the incidence of CIN in comparison with patients who did not receive CM. KEY POINTS : • The contrast medium used for multidetector CT can induce nephropathy. • Contrast-induced nephropathy (CIN) developed in 6.1 % of patients with renal insufficiency. • However, nephropathy developed in 5.8 % of similar patients not receiving contrast medium. • Thus, the risk of CIN associated with MDCT appears to be low. • Special care should still be taken in patients with renal insufficiency.
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