Evidence map›Paper›PMID 22548564›Full record

ReviewAnnals of the New York Academy of Sciences2012

Cardiovascular defense challenges at the basic, clinical, and population levels.

Jason C Kovacic, Jose M Castellano, Valentin Fuster

Abstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jason C KovacicZena and Michael A. Wiener Cardiovascular Institute.
Jose M CastellanoZena and Michael A. Wiener Cardiovascular Institute.
Valentin FusterZena and Michael A. Wiener Cardiovascular Institute.

Funding

TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Cellular and molecular mechanisms of endothelial repair and atherosclerosisK08HL111330 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVACIC, JASON CIRIL · 2012 to 2016
$647k
NHLBI NIH HHS 1K08HL111330-01NHLBI NIH HHS K08 HL111330NHLBI NIH HHS T32 HL007824
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is now the leading cause of mortality worldwide. Particularly in low and middle income countries, rapid urbanization and secondary factors, such as increasing obesity, poor diet, and lack of exercise, have combined to propel CVD into this position. Given the enormous scope of this problem and the complex cultural, societal, and political issues that are involved, an equally sophisticated and multipronged approach is required to combat CVD at the global level. In this review, we outline the basic, clinical, and population level challenges that we face in defending ourselves against this disease.

Indexed as

AgingCardiovascular DiseasesCholesterol, HDLGlobal HealthHealth PromotionHumansRisk FactorsCholesterol, HDL

Identifiers

PMID22548564
PMCPMC3752384

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.