ReviewNeural plasticity2012
Plasticity of adult sensorimotor system in severe brain infarcts: challenges and opportunities.
Review in Neural plasticity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial.PloS one · 2013Trial
- High Technology-Assisted Rehabilitation Based on Neuropsychological Assessments in a Case of Severe Acquired Brain Injury.Case reports in neurological medicine · 2025Article
- A neurocognitive approach for recovering upper extremity movement following subacute stroke: a randomized controlled pilot study.Journal of physical therapy science · 2017Article
- Upper Limb Immobilisation: A Neural Plasticity Model with Relevance to Poststroke Motor Rehabilitation.Neural plasticity · 2016Review
- A case to be made: theoretical and empirical arguments for the need to consider fatigue in post-stroke motor rehabilitation.Neural regeneration research · 2015Article
- Altered contralateral sensorimotor system organization after experimental hemispherectomy: a structural and functional connectivity study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2015Article
- CI Therapy is Beneficial to Patients with Chronic Low-Functioning Hemiparesis after Stroke.Frontiers in neurology · 2014Article
- Biomarkers and predictors of restorative therapy effects after stroke.Current neurology and neuroscience reports · 2013Review
- Contralateral cortical role on functional recovery in a rat model of hemiplegia.EXCLI journal · 2013Article
- Electroacupuncture-Induced Neuroprotection against Cerebral Ischemia in Rats: Role of the Dopamine D2 Receptor.Evidence-based complementary and alternative medicine : eCAM · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Functional reorganization forms the critical mechanism for the recovery of function after brain damage. These processes are driven by inherent changes within the central nervous system (CNS) triggered by the insult and further depend on the neural input the recovering system is processing. Therefore these processes interact with not only the interventions a patient receives, but also the activities and behaviors a patient engages in. In recent years, a wide range of research programs has addressed the association between functional reorganization and the spontaneous and treatment-induced recovery. The bulk of this work has focused on upper-limb and hand function, and today there are new treatments available that capitalize on the neuroplasticity of the brain. However, this is only true for patients with mild to moderated impairments; for those with very limited hand function, the basic understanding is much poorer and directly translates into limited treatment opportunities for these patients. The present paper aims to highlight the knowledge gap on severe stroke with a brief summary of the literature followed by a discussion of the challenges involved in the study and treatment of severe stroke and poor long-term outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.