Trial reportJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2012
Impact on quality of life after pancreatoduodenectomy: a prospective study comparing preoperative and postoperative scores.
Trial report in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early enteral nutrition after pancreatoduodenectomy: a meta-analysis of randomized controlled trials.Langenbeck's archives of surgery · 2013Pooled it
- Epidurals in Pancreatic Resection Outcomes (E-PRO) study: protocol for a randomised controlled trial.BMJ open · 2018Trial
- A prospective study of patient reported outcomes in pancreatic and peri-ampullary malignancy.World journal of surgery · 2013Trial
- Preoperative Quality of Life as Predictor of Postoperative Early Recurrence and Overall Survival in Patients with Pancreatic and Periampullary Adenocarcinoma.Journal of gastrointestinal cancer · 2026Article
- Do Complications After Pancreatoduodenectomy Have an Impact on Long-Term Quality of Life and Functional Outcomes?Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Quality of life after pancreatic surgery.World journal of gastroenterology · 2024Review
- Article
- Short-term clinical outcomes of enteral nutrition versus parenteral nutrition after surgery for pancreatic cancer: a meta-analysis.Translational cancer research · 2019Article
- Determinants and prognostic value of quality of life in patients with pancreatic ductal adenocarcinoma.European journal of cancer (Oxford, England : 1990) · 2018Article
- Postoperative outcome and quality of life after surgery for FAP-associated duodenal adenomatosis.Langenbeck's archives of surgery · 2018Article
- Burden of cancer pain in developing countries: a narrative literature review.ClinicoEconomics and outcomes research : CEOR · 2018Review
- Quality of Life Variables Assessment, Before and After Pancreatoduodenectomy (PD): Prospective Study.Global journal of health science · 2015Article
- Cost-effectiveness of diagnostic laparoscopy for assessing resectability in pancreatic and periampullary cancer.BMC gastroenterology · 2015Article
- Cost-effectiveness of preoperative biliary drainage for obstructive jaundice in pancreatic and periampullary cancer.The Journal of surgical research · 2015Article
- Early and late postoperative changes in the quality of life after pancreatic surgery.Langenbeck's archives of surgery · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFew studies compare the direct impact of pancreatoduodenectomy (PD) on the patient's quality of life (QOL). The effect of PD in QOL, comparing the preoperative vs. postoperative status, was analyzed.
methodA prospective single-center study was performed. PD patients in a 2-year period were included. A general QOL instrument was applied preoperative, 1, 3, 6, and 12 months after surgery and compared with national norms.
resultsThirty-seven patients were recruited. Twenty of 37 were female. Ampullary carcinoma 14/37, ductal adenocarcinoma in 9/37, and other malignant neoplasms 14/37 were diagnosed. Mortality was absent; 48.6% had complications, 13.5 % required reoperation. Three (median) and 4 (mode) questionnaires were answered per individual. 85 % answered the last questionnaire. 4/37 had cancer related death before a year. Median follow-up was 29 (3-72) months. QOL diminished a month after surgery, physical function (67 vs 40, p<0.0001) and emotional role (37 vs 17, p<0.032) did so significantly. Three months after surgery QOL improved yet not significantly. Six and 12 months postoperatively, physical role (9 vs 49, p=0.001), physical pain (51 vs 71, p=0.01), social function (52 vs 63, p=0.014), vitality (54 vs 64, p=0.018), and emotional role (41 vs 69, p=0.006) improved significantly. DISCUSSION: PD has a favorable impact in quality of life as demonstrated by the improvement of most parameters assessed in the postoperative period.
Indexed as
Identifiers
22547348What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.