Evidence map›Paper›PMID 22546938›Full record

ReviewRNA biology2012

Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis.

Kristine Arnvig, Douglas Young

Open access · hybridAbstract readReview
In one paragraph

Review in RNA biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.

  1. Meta-analysis reveals a core iron-responsive gene signature in Mycobacterium tuberculosis linking siderophore biosynthesis, virulence, and metabolic adaptation.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Pooled it
  2. The Cold Shock Protein CspB fromInternational journal of molecular sciences · 2026
    Article
  3. Frontiers in cellular and infection microbiology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Heliyon · 2023
    Article
  10. Small RNA MTS1338 Configures a Stress Resistance Signature inInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Close Related Drug-Resistance Beijing Isolates ofInternational journal of molecular sciences · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Transcriptional regulation and drug resistance inFrontiers in cellular and infection microbiology · 2022
    Review
  19. Review
  20. Microorganisms · 2021
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Kristine ArnvigDivision of Mycobacterial Research, MRC National Institute for Medical Research, London, UK. karnvig@nimr.mrc.ac.uk
Douglas Young
MRC London Institute of Medical Sciences · GBNational Institute for Medical Research · TZ

Funding

Medical Research Council MC_U117581288
6 · The paper itself

Abstract

It is estimated that one third of the human population is infected with Mycobacterium tuberculosis. Efforts to understand the molecular basis of its gene regulation have been focused on identification of protein encoding genes and regulons implicated in pathogenesis. Recently, a number of studies have described the identification of several non-coding RNAs that are likely to contribute significantly to the regulatory networks responsible for adaptation and virulence in M. tuberculosis. We have reviewed emerging information on the presence and abundance of different types of non-coding RNA in M. tuberculosis and consider their potential contribution to the adaptive responses that underlie disease pathogenesis.

Indexed as

AnimalsBacterial ProteinsGene Expression Regulation, BacterialGenes, BacterialHost-Pathogen InteractionsHumansMycobacterium tuberculosisRiboswitchRNA, BacterialRNA, Small UntranslatedStress, PhysiologicalTuberculosisVirulenceBacterial ProteinsRiboswitchRNA, BacterialRNA, Small Untranslated

Identifiers

PMID22546938
PMCPMC3384566
OpenAlexW1971997781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.