Evidence map›Paper›PMID 22546920›Full record

ArticleComparative medicine2012

Chronic diseases in captive geriatric female Chimpanzees (Pan troglodytes).

Elizabeth A Nunamaker, D Rick Lee, Michael L Lammey

Open access · greenAbstract read
In one paragraph

Article in Comparative medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Minimal Evidence of Inflammaging in Naturalistic Chimpanzee Populations.American journal of biological anthropology · 2026
    Article
  2. Article
  3. Review
  4. How Sanctuary Chimpanzees (Animals : an open access journal from MDPI · 2023
    Article
  5. Integrating Reference Intervals into Chimpanzee Welfare Research.Animals : an open access journal from MDPI · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Differences in Behavior Between Elderly and Nonelderly Captive Chimpanzees and the Effects of the Social Environment.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  14. Article
  15. Article
  16. Animal welfare (South Mimms, England) · 2018
    Article
  17. Non-human primates as a model for aging.Biochimica et biophysica acta. Molecular basis of disease · 2018
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elizabeth A NunamakerSchool of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA. enunamak@uic.edu
D Rick Lee
Michael L Lammey
Purdue University West Lafayette · US

Funding

ZWITTERION SURFACTANT DDMAB FOR IMPROV STABIL OF PROTEINP41RR001209 · NCRR · STANFORD UNIVERSITY · PI REESE, MICHAEL LLOYD · 1985 to 2011
$38.9M
NCRR NIH HHS N02-RR-1-209
6 · The paper itself

Abstract

The current aging population of captive chimpanzees is expected to develop age-related diseases and present new challenges to providing their veterinary care. Spontaneous heart disease and sudden cardiac death are the main causes of death in chimpanzees (especially of male animals), but little is known about the relative frequency of other chronic diseases. Furthermore, female chimpanzees appear to outlive the males and scant literature addresses clinical conditions that affect female chimpanzees. Here we characterize the types and prevalence of chronic disease seen in geriatric (older than 35 y) female chimpanzees in the colony at Alamogordo Primate Facility. Of the 16 female chimpanzees that fit the age category, 87.5% had some form of chronic age-related disease. Cardiovascular-related disease was the most common (81.25%) followed by metabolic syndrome (43.75%) and renal disease (31.25%). These data show the incidence of disease in geriatric female chimpanzees and predict likely medical management challenges associated with maintaining an aging chimpanzee population.

Indexed as

AgingPan troglodytesAge FactorsAnimalsApe DiseasesBiomarkersBlood GlucoseBlood PressureBlood Urea NitrogenCardiovascular DiseasesChronic DiseaseCreatinineEchocardiographyElectrocardiographyFemaleGlycated HemoglobinBiomarkersBlood GlucoseCreatinineGlycated HemoglobinLipidsSerum Albumin

Identifiers

PMID22546920
PMCPMC3318251
OpenAlexW1536329555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.