Evidence map›Paper›PMID 22545198›Full record

ArticleTranslational neuroscience2012

Spherical harmonic analysis of cortical complexity in autism and dyslexia.

Emily L Williams, Ayman El-Baz, Matthew Nitzken, Andrew E Switala, Manuel F Casanova

Abstract read
In one paragraph

Article in Translational neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. The Neurodevelopment of Autism from Infancy Through Toddlerhood.Neuroimaging clinics of North America · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emily L WilliamsDepartment of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY 40202, USA.
Ayman El-Baz
Matthew Nitzken
Andrew E Switala
Manuel F Casanova

Funding

Building a Selective Inhibitory Control Tone in Autism: An rTMS StudyR01MH086784 · NIMH · UNIVERSITY OF LOUISVILLE · PI CASANOVA, MANUEL F · 2009 to 2012
$884k
Gross morphological correlates to the minicolumnopathy of autismR01HD065279 · NICHD · UNIVERSITY OF LOUISVILLE · PI CASANOVA, MANUEL F · 2009 to 2010
$547k
NICHD NIH HHS R01 HD065279NIMH NIH HHS R01 MH086784
6 · The paper itself

Abstract

Alterations in gyral form and complexity have been consistently noted in both autism and dyslexia. In this present study, we apply spherical harmonics, an established technique which we have exapted to estimate surface complexity of the brain, in order to identify abnormalities in gyrification between autistics, dyslexics, and controls. On the order of absolute surface complexity, autism exhibits the most extreme phenotype, controls occupy the intermediate ranges, and dyslexics exhibit lesser surface complexity. Here, we synthesize our findings which demarcate these three groups and review how factors controlling neocortical proliferation and neuronal migration may lead to these distinctive phenotypes.

Identifiers

PMID22545198
PMCPMC3336871

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.