ArticleScientific reports2011
Intrinsic noise alters the frequency spectrum of mesoscopic oscillatory chemical reaction systems.
Article in Scientific reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Understanding the physical mechanism of intrinsic noise inside viscous isotropic solids.Scientific reports · 2022Article
- pSSAlib: The partial-propensity stochastic chemical network simulator.PLoS computational biology · 2017Article
- A minimal model of burst-noise induced bistability.PloS one · 2017Article
- Activity induces traveling waves, vortices and spatiotemporal chaos in a model actomyosin layer.Scientific reports · 2016Article
- Sustainability of Transient Kinetic Regimes and Origins of Death.Scientific reports · 2016Article
- Promoters Architecture-Based Mechanism for Noise-Induced Oscillations in a Single-Gene Circuit.PloS one · 2016Article
- Modeling and simulation of biological systems from image data.BioEssays : news and reviews in molecular, cellular and developmental biology · 2013Article
- Discreteness-induced concentration inversion in mesoscopic chemical systems.Nature communications · 2012Article
- Intrinsic noise analyzer: a software package for the exploration of stochastic biochemical kinetics using the system size expansion.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mesoscopic oscillatory reaction systems, for example in cell biology, can exhibit stochastic oscillations in the form of cyclic random walks even if the corresponding macroscopic system does not oscillate. We study how the intrinsic noise from molecular discreteness influences the frequency spectrum of mesoscopic oscillators using as a model system a cascade of coupled Brusselators away from the Hopf bifurcation. The results show that the spectrum of an oscillator depends on the level of noise. In particular, the peak frequency of the oscillator is reduced by increasing noise, and the bandwidth increased. Along a cascade of coupled oscillators, the peak frequency is further reduced with every stage and also the bandwidth is reduced. These effects can help understand the role of noise in chemical oscillators and provide fingerprints for more reliable parameter identification and volume measurement from experimental spectra.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.