ArticlePloS one2012
mRNA-Seq analysis of the Pseudoperonospora cubensis transcriptome during cucumber (Cucumis sativus L.) infection.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 59 citations in OpenAlex.
- Identification ofMycobiology · 2024Article
- Garlic Volatile Diallyl Disulfide Induced Cucumber Resistance to Downy Mildew.International journal of molecular sciences · 2021Article
- Transcriptome Profiling of Cucumber (International journal of molecular sciences · 2021Article
- Contrasting transcriptional responses to Fusarium virguliforme colonization in symptomatic and asymptomatic hosts.The Plant cell · 2021Article
- Article
- The Effector Repertoire of the Hop Downy Mildew PathogenFrontiers in genetics · 2020Article
- Comparative transcriptomic analyses of powdery mildew resistant and susceptible cultivated cucumber (PeerJ · 2020Article
- Conservation and Divergence in the Meiocyte sRNAomes of Arabidopsis, Soybean, and Cucumber.Plant physiology · 2020Article
- Resurgence of cucurbit downy mildew in the United States: Insights from comparative genomic analysis ofEcology and evolution · 2017Article
- Article
- Dual RNA-Sequencing of Eucalyptus nitens during Phytophthora cinnamomi Challenge Reveals Pathogen and Host Factors Influencing Compatibility.Frontiers in plant science · 2016Article
- Oomycete interactions with plants: infection strategies and resistance principles.Microbiology and molecular biology reviews : MMBR · 2015Review
- Article
- Transcriptomic analysis of the phytopathogenic oomycete Phytophthora cactorum provides insights into infection-related effectors.BMC genomics · 2014Article
- Bioinformatic characterisation of genes encoding cell wall degrading enzymes in the Phytophthora parasitica genome.BMC genomics · 2014Article
- Comparative analyses of two Geraniaceae transcriptomes using next-generation sequencing.BMC plant biology · 2013Article
- From pathogen genomes to host plant processes: the power of plant parasitic oomycetes.Genome biology · 2013Review
- Article
- RNA-Seq analysis reveals candidate genes for ontogenic resistance in Malus-Venturia pathosystem.PloS one · 2013Article
- Dynamics and innovations within oomycete genomes: insights into biology, pathology, and evolution.Eukaryotic cell · 2012Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pseudoperonospora cubensis, an oomycete, is the causal agent of cucurbit downy mildew, and is responsible for significant losses on cucurbit crops worldwide. While other oomycete plant pathogens have been extensively studied at the molecular level, Ps. cubensis and the molecular basis of its interaction with cucurbit hosts has not been well examined. Here, we present the first large-scale global gene expression analysis of Ps. cubensis infection of a susceptible Cucumis sativus cultivar, 'Vlaspik', and identification of genes with putative roles in infection, growth, and pathogenicity. Using high throughput whole transcriptome sequencing, we captured differential expression of 2383 Ps. cubensis genes in sporangia and at 1, 2, 3, 4, 6, and 8 days post-inoculation (dpi). Additionally, comparison of Ps. cubensis expression profiles with expression profiles from an infection time course of the oomycete pathogen Phytophthora infestans on Solanum tuberosum revealed similarities in expression patterns of 1,576-6,806 orthologous genes suggesting a substantial degree of overlap in molecular events in virulence between the biotrophic Ps. cubensis and the hemi-biotrophic P. infestans. Co-expression analyses identified distinct modules of Ps. cubensis genes that were representative of early, intermediate, and late infection stages. Collectively, these expression data have advanced our understanding of key molecular and genetic events in the virulence of Ps. cubensis and thus, provides a foundation for identifying mechanism(s) by which to engineer or effect resistance in the host.
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