ArticlePloS one2012
HRS1 acts as a negative regulator of abscisic acid signaling to promote timely germination of Arabidopsis seeds.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
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- Genome-Scale Investigation ofInternational journal of molecular sciences · 2022Article
- ZEITLUPE Promotes ABA-Induced Stomatal Closure in Arabidopsis andFrontiers in plant science · 2022Article
- Plant NIGT1/HRS1/HHO Transcription Factors: Key Regulators with Multiple Roles in Plant Growth, Development, and Stress Responses.International journal of molecular sciences · 2021Review
- GARP transcription factors repress Arabidopsis nitrogen starvation response via ROS-dependent and -independent pathways.Journal of experimental botany · 2021Article
- A GARP transcription factor anther dehiscence defected 1 (OsADD1) regulates rice anther dehiscence.Plant molecular biology · 2019Article
- Asperlin Stimulates Energy Expenditure and Modulates Gut Microbiota in HFD-Fed Mice.Marine drugs · 2019Article
- Cordycepin promotes browning of white adipose tissue through an AMP-activated protein kinase (AMPK)-dependent pathway.Acta pharmaceutica Sinica. B · 2019Article
- Nitric oxide responses in Arabidopsis hypocotyls are mediated by diverse phytohormone pathways.Journal of experimental botany · 2018Article
- The GARP/MYB-related grape transcription factor AQUILO improves cold tolerance and promotes the accumulation of raffinose family oligosaccharides.Journal of experimental botany · 2018Article
- The aqueous extract of Phellinus igniarius (SH) ameliorates dextran sodium sulfate-induced colitis in C57BL/6 mice.PloS one · 2018Article
- Comparative Leaf and Root Transcriptomic Analysis of two Rice Japonica Cultivars Reveals Major Differences in the Root Early Response to Osmotic Stress.Rice (New York, N.Y.) · 2016Article
- AtNIGT1/HRS1 integrates nitrate and phosphate signals at the Arabidopsis root tip.Nature communications · 2015Article
- Cordycepin activates AMP-activated protein kinase (AMPK) via interaction with the γ1 subunit.Journal of cellular and molecular medicine · 2014Article
- Chlorogenic acid protects against atherosclerosis in ApoE-/- mice and promotes cholesterol efflux from RAW264.7 macrophages.PloS one · 2014Article
- Modulation of lipogenesis and glucose consumption in HepG2 cells and C2C12 myotubes by sophoricoside.Molecules (Basel, Switzerland) · 2013Article
- Differential control of seed primary dormancy in Arabidopsis ecotypes by the transcription factor SPATULA.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this work, we conducted functional analysis of Arabidopsis HRS1 gene in order to provide new insights into the mechanisms governing seed germination. Compared with wild type (WT) control, HRS1 knockout mutant (hrs1-1) exhibited significant germination delays on either normal medium or those supplemented with abscisic acid (ABA) or sodium chloride (NaCl), with the magnitude of the delay being substantially larger on the latter media. The hypersensitivity of hrs1-1 germination to ABA and NaCl required ABI3, ABI4 and ABI5, and was aggravated in the double mutant hrs1-1abi1-2 and triple mutant hrs1-1hab1-1abi1-2, indicating that HRS1 acts as a negative regulator of ABA signaling during seed germination. Consistent with this notion, HRS1 expression was found in the embryo axis, and was regulated both temporally and spatially, during seed germination. Further analysis showed that the delay of hrs1-1 germination under normal conditions was associated with reduction in the elongation of the cells located in the lower hypocotyl (LH) and transition zone (TZ) of embryo axis. Interestingly, the germination rate of hrs1-1 was more severely reduced by the inhibitor of cell elongation, and more significantly decreased by the suppressors of plasmalemma H(+)-ATPase activity, than that of WT control. The plasmalemma H(+)-ATPase activity in the germinating seeds of hrs1-1 was substantially lower than that exhibited by WT control, and fusicoccin, an activator of this pump, corrected the transient germination delay of hrs1-1. Together, our data suggest that HRS1 may be needed for suppressing ABA signaling in germinating embryo axis, which promotes the timely germination of Arabidopsis seeds probably by facilitating the proper function of plasmalemma H(+)-ATPase and the efficient elongation of LH and TZ cells.
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