Evidence map›Paper›PMID 22545033›Full record

ArticleCurrent medical imaging reviews2011

Acoustic Radiation Force Impulse (ARFI) Imaging: a Review.

Kathy Nightingale

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current medical imaging reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02470000 (Treatment of Chronic Myofascial Pain Syndrome Over Neck by Using Intravascular Laser Irradiation of Blood), which is not on this map. Cited by 143 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed, 1 pooled it
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02470000 naunknown statusnot on this mapstarted 2014, after this paper: background citation

Treatment of Chronic Myofascial Pain Syndrome Over Neck by Using Intravascular Laser Irradiation of Blood

TypeinterventionalSponsorChang Gung Memorial HospitalRan2014 to 2016Enrolled36ConditionsMyofacial Pain SyndromesArmsIntravascular laser irradiation of blood (ILIB), Transcutaneous electrical nerve stimulation, Stretching exercise
3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 1 synthesis or guideline pooled it, 398 citations in OpenAlex.

  1. Pooled it
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  9. Sono-Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
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83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kathy NightingaleDepartment of Biomedical Engineering, Duke University Box 90281, Durham, NC 27708-0281, USA telephone:(919)660-5175, fax:(919)684-4488, kathy.nightingaleduke.edu.
Duke University · US

Funding

REMOTE PALPATION IMAGING IN THE BREASTR01EB002132 · NIBIB · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2003 to 2015
$4.9M
Radiation Force Imaging of Prostate Cancer and Guidance of Biopsy ProceduresR01CA142824 · NCI · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2010 to 2021
$4.4M
Acoustic Radiation Force Imaging of Colorectal TissuesR01CA114075 · NCI · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2005 to 2009
$1.4M
NCI NIH HHS R01 CA114075NCI NIH HHS R01 CA142824NIBIB NIH HHS R01 EB002132
6 · The paper itself

Abstract

Acoustic radiation force based elasticity imaging methods are under investigation by many groups. These methods differ from traditional ultrasonic elasticity imaging methods in that they do not require compression of the transducer, and are thus expected to be less operator dependent. Methods have been developed that utilize impulsive (i.e. < 1 ms), harmonic (pulsed), and steady state radiation force excitations. The work discussed herein utilizes impulsive methods, for which two imaging approaches have been pursued: 1) monitoring the tissue response within the radiation force region of excitation (ROE) and generating images of relative differences in tissue stiffness (Acoustic Radiation Force Impulse (ARFI) imaging); and 2) monitoring the speed of shear wave propagation away from the ROE to quantify tissue stiffness (Shear Wave Elasticity Imaging (SWEI)). For these methods, a single ultrasound transducer on a commercial ultrasound system can be used to both generate acoustic radiation force in tissue, and to monitor the tissue displacement response. The response of tissue to this transient excitation is complicated and depends upon tissue geometry, radiation force field geometry, and tissue mechanical and acoustic properties. Higher shear wave speeds and smaller displacements are associated with stiffer tissues, and slower shear wave speeds and larger displacements occur with more compliant tissues. ARFI images have spatial resolution comparable to that of B-mode, often with greater contrast, providing matched, adjunctive information. SWEI images provide quantitative information about the tissue stiffness, typically with lower spatial resolution. A review these methods and examples of clinical applications are presented herein.

Identifiers

PMID22545033
PMCPMC3337770
OpenAlexW1971183419

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.