ArticleEuropean child & adolescent psychiatry2012
Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder.
Article in European child & adolescent psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 162 citations in OpenAlex.
- Pharmacological Interventions for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents with Tourette Disorder: A Systematic Review and Network Meta-Analysis.Journal of child and adolescent psychopharmacology · 2024Pooled it
- Living with tics: reduced impairment and improved quality of life for youth with chronic tic disorders.Psychiatry research · 2015Trial
- The effect of calendar month on tic severity in children and youth with Tourette syndrome.BJPsych open · 2026Article
- Early developmental milestones associated with tics and psychopathological comorbidity: An EMTICS study.European child & adolescent psychiatry · 2025Observational
- Tic-related behaviors in Celsr3 mutant mice are contributed by alterations of striatal DMolecular psychiatry · 2025Article
- Network hub changes in the pars opercularis indicate impaired inhibition in tic disorder patients.Acta neuropsychiatrica · 2025Article
- Risk of Sleep Disorders among Patients with Tourette Syndrome: A Population-Based Cohort Study in Taiwan.International journal of medical sciences · 2025Article
- Validation and assessment of the self-injurious behavior scale for tic disorders (SIBS-T).Scientific reports · 2024Article
- Circulating retinol and 25(OH)D contents and their association with symptoms in children with chronic tic disorders.European child & adolescent psychiatry · 2024Article
- Sleep Disorders, Sleep Medication Use, and Predictors of Sleep Disturbance in Children with Persistent Tic Disorders.Children's health care : journal of the Association for the Care of Children's Health · 2024Article
- Tic disorders in children and adolescents: does the clinical presentation differ in males and females? A report by the EMTICS group.European child & adolescent psychiatry · 2022Article
- Enhanced habit formation in Tourette patients explained by shortcut modulation in a hierarchical cortico-basal ganglia model.Brain structure & function · 2022Article
- Developmental impact of glutamate transporter overexpression on dopaminergic neuron activity and stereotypic behavior.Molecular psychiatry · 2022Article
- Academic, Interpersonal, Recreational, and Family Impairment in Children with Tourette Syndrome and Attention-Deficit/Hyperactivity Disorder.Child psychiatry and human development · 2022Article
- Revisiting the structure of the Yale Global Tic Severity Scale (YGTSS) in a sample of Chinese children with tic disorders.BMC psychiatry · 2021Article
- Current Management of Tics and Tourette Syndrome: Behavioral, Pharmacologic, and Surgical Treatments.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020Review
- Aggressive symptoms in children with tic disorders.European child & adolescent psychiatry · 2020Article
- Current Status, Diagnosis, and Treatment Recommendation for Tic Disorders in China.Frontiers in psychiatry · 2020Review
- Examining the functional activity of different obsessive-compulsive symptom dimensions in Tourette syndrome.NeuroImage. Clinical · 2020Article
- Tic disorders revisited: introduction of the term "tic spectrum disorders".European child & adolescent psychiatry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
Abstract
Chronic tic disorders (TD) are consistently found to have high rates of comorbidity with obsessive-compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD). The purpose of this study is to compare the severity of TD only to TD with comorbid OCD or ADHD based on severity of tics, measures of psychopathology and additional comorbid diagnoses. Baseline data from 158 youth with a chronic TD who participated in two longitudinal studies were examined. Fifty-three percent (N = 85) of the youth also met criteria for a diagnosis of OCD, 38.6 % (n = 61) met criteria for ADHD and 24.1 % (N = 38) met criteria for both. Measures of interest addressed severity of tics, symptoms of anxiety, depression, ADHD, psychosocial stress, global functioning and the presence of comorbid diagnoses. Youth with comorbid TD and OCD were characterized by more severe tics, increased levels of depressive and anxious symptoms, heightened psychosocial stress and poorer global functioning. Youth with comorbid TD and ADHD did not differ from those with TD alone on measures of tic severity, but experienced greater psychosocial stress and poorer global functioning. Subjects with comorbid TD and OCD had more internalizing disorders than those without OCD, while those with comorbid ADHD were more likely to meet criteria for oppositional defiant disorder. TD with OCD is a more severe subtype of TD than TD without OCD. TD with ADHD is associated with higher psychosocial stress and more externalizing behaviors. Further research is needed into the underlying relationships between these closely associated conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.