Evidence map›Paper›PMID 22543227›Full record

ArticleBone2012

Socioeconomic status over the life-course and adult bone mineral density: the Midlife in the U.S. Study.

Carolyn J Crandall, Sharon Stein Merkin, Teresa E Seeman, Gail A Greendale, Neil Binkley, Arun S Karlamangla

Open access · greenAbstract read
In one paragraph

Article in Bone, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 46 citations in OpenAlex.

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  15. Factors influencing peak bone mass gain.Frontiers of medicine · 2021
    Review
  16. Article
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  19. Socioeconomic status and bone mineral density in adults by race/ethnicity and gender: the Louisiana osteoporosis study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Carolyn J CrandallDivision of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, USA. ccrandall@mednet.ucla.edu
Sharon Stein Merkin
Teresa E Seeman
Gail A Greendale
Neil Binkley
Arun S Karlamangla
University of California, Los Angeles · USUniversity of Wisconsin–Madison · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
ZDV &3TC NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFECTED INFANTS &M01RR000865 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WASHINGTON, ARNOLD E. · 1985 to 2011
$43.4M
UCLA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR033176 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2011 to 2011
$15.5M
Lifespan Psychosocial Profiles and Biological Pathways to Bone StrengthR01AG033067 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CRANDALL, CAROLYN JANET, KARLAMANGLA, ARUN S · 2009 to 2012
$1.4M
Histories of Social Engagement and Cognitive FunctioningR01AG032271 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SEEMAN, TERESA E · 2009 to 2010
$999k
NCATS NIH HHS UL1 TR000124NCRR NIH HHS M01 RR000865NCRR NIH HHS M01-RR000865NCRR NIH HHS UL1 RR033176NIA NIH HHS 1R01AG033067NIA NIH HHS P01 AG020166NIA NIH HHS P01-AG-020166NIA NIH HHS R01 AG032271NIA NIH HHS R01-AG-032271NIA NIH HHS R01 AG033067
6 · The paper itself

Abstract

purposeAdult bone mass depends on acquisition in childhood and decline in adulthood, and may be influenced by socioeconomic conditions over the entire life course.

methodsWe examined associations of bone mineral density (BMD) in adulthood with life course socioeconomic status in 729 participants in the Midlife in the United States Biomarker Project, adjusting for age, menopausal transition stage, race, gender, body weight, smoking, physical activity in several life stages, and research site. Primary predictors were a) childhood socioeconomic advantage score (including parental education, self-rated financial status relative to others, not being on welfare), b) adult education level (no college vs. some college vs. college graduate), and c) adult current financial advantage score (including family-adjusted poverty to income ratio, self-assessed current financial situation, having enough money to meet needs, ease in paying bills).

resultsMean age was 56.9 (range 34-85) years. After adjustment for covariates, childhood socioeconomic advantage and adult education level were positively associated with lumbar spine BMD: 0.27 standard deviations (SD) higher at 90th compared to 10th percentile of childhood advantage score (P=0.009), and 0.24 SD higher in college graduates compared to participants without college education (P=0.01). Adult current financial advantage was not associated with lumbar spine BMD. None of the three socioeconomic indicators was significantly associated with femoral neck BMD.

conclusionsChildhood socioeconomic advantage and adult education level were associated with higher adult lumbar spine BMD. Current financial advantage was not associated with BMD. Childhood socioeconomic factors may influence acquisition of lumbar BMD.

Indexed as

Social ClassAgedBone DensityFemaleFemur NeckHumansMaleMiddle AgedPovertyUnited States

Identifiers

PMID22543227
PMCPMC3371160
OpenAlexW2100455679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.