ArticleGenetics2012
Megabase-scale inversion polymorphism in the wild ancestor of maize.
Article in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 112 citations in OpenAlex.
- What has population genomics told us about the dynamics of selection and plant adaptation?Molecular biology and evolution · 2026Review
- A trio-binning approach for genome assembly reveals extensive structural variation between two Cannabis cultivars: Punto Rojo and Cherry Pie.G3 (Bethesda, Md.) · 2026Article
- Limited population structure but signals of recent selection in introduced African Fig Fly (Zaprionus indianus) in North America.G3 (Bethesda, Md.) · 2025Article
- The Evolution of Locally Adaptive Chromosome Inversions in Mimulus guttatus.Molecular ecology · 2025Article
- Environmental genomic selection to leverage polygenic local adaptation in barley landraces.Communications biology · 2025Article
- Article
- Genomic determinants, architecture, and constraints in drought-related traits in Corymbia calophylla.BMC genomics · 2024Article
- Chromosomal Inversions and the Demography of Speciation in Drosophila montana and Drosophila flavomontana.Genome biology and evolution · 2024Article
- Genomics of plant speciation.Plant communications · 2023Review
- Chromosomal inversion polymorphisms shape the genomic landscape of deer mice.Nature ecology & evolution · 2022Article
- Genome sequencing reveals evidence of adaptive variation in the genus Zea.Nature genetics · 2022Article
- Temperature-associated selection linked to putative chromosomal inversions in king scallop (Proceedings. Biological sciences · 2022Article
- The evolutionary patterns of barley pericentromeric chromosome regions, as shaped by linkage disequilibrium and domestication.The Plant journal : for cell and molecular biology · 2022Article
- A chromosomal inversion contributes to divergence in multiple traits between deer mouse ecotypes.Science (New York, N.Y.) · 2022Article
- Genomic structural variants constrain and facilitate adaptation in natural populations ofProceedings of the National Academy of Sciences of the United States of America · 2021Article
- A Draft Genome of the Ginger SpeciesGenes · 2021Article
- Locally Adaptive Inversions Modulate Genetic Variation at Different Geographic Scales in a Seaweed Fly.Molecular biology and evolution · 2021Article
- The genomic basis of geographic differentiation and fiber improvement in cultivated cotton.Nature genetics · 2021Article
- Detection of ploidy and chromosomal aberrations in commercial oil palm using high-throughput SNP markers.Planta · 2021Article
- Extensive haplotypes are associated with population differentiation and environmental adaptability in Upland cotton (Gossypium hirsutum).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chromosomal inversions are thought to play a special role in local adaptation, through dramatic suppression of recombination, which favors the maintenance of locally adapted alleles. However, relatively few inversions have been characterized in population genomic data. On the basis of single-nucleotide polymorphism (SNP) genotyping across a large panel of Zea mays, we have identified an ∼50-Mb region on the short arm of chromosome 1 where patterns of polymorphism are highly consistent with a polymorphic paracentric inversion that captures >700 genes. Comparison to other taxa in Zea and Tripsacum suggests that the derived, inverted state is present only in the wild Z. mays subspecies parviglumis and mexicana and is completely absent in domesticated maize. Patterns of polymorphism suggest that the inversion is ancient and geographically widespread in parviglumis. Cytological screens find little evidence for inversion loops, suggesting that inversion heterozygotes may suffer few crossover-induced fitness consequences. The inversion polymorphism shows evidence of adaptive evolution, including a strong altitudinal cline, a statistical association with environmental variables and phenotypic traits, and a skewed haplotype frequency spectrum for inverted alleles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.