ArticleGenetics2012
Disentangling the roles of history and local selection in shaping clinal variation of allele frequencies and gene expression in Norway spruce (Picea abies).
Article in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 154 citations in OpenAlex.
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- Contrasting Patterns of Local Adaptation and Adaptive Potential Under Climate Change for Old-Growth and Planted Stands of Norway Spruce (Evolutionary applications · 2026Article
- Transcriptome characterisation and population genetics ofBiodiversity data journal · 2025Article
- Local climate and vernalization sensitivity predict the latitudinal patterns of flowering onset in the crop wild relative Linum bienne Mill.Annals of botany · 2024Article
- Assembly and annotation of the black spruce genome provide insights on spruce phylogeny and evolution of stress response.G3 (Bethesda, Md.) · 2023Article
- From common gardens to candidate genes: exploring local adaptation to climate in red spruce.The New phytologist · 2023Article
- Molecular mechanisms of flowering phenology in trees.Forestry research · 2023Review
- Teasing apart the joint effect of demography and natural selection in the birth of a contact zone.The New phytologist · 2022Article
- Genetic diversity of Norway spruce ecotypes assessed by GBS-derived SNPs.Scientific reports · 2021Article
- Genome-wide shifts in climate-related variation underpin responses to selective breeding in a widespread conifer.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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- Photoperiod Control of Plant Growth: Flowering Time Genes Beyond Flowering.Frontiers in plant science · 2021Review
- Genomic Adaptive Evolution of Sand Rice (Frontiers in genetics · 2021Article
- Evolvability of Drought Response in Four Native and Non-native Conifers: Opportunities for Forest and Genetic Resource Management in Europe.Frontiers in plant science · 2021Article
- Genomics of Clinal Local Adaptation inG3 (Bethesda, Md.) · 2020Article
- Ecological Factors Generally Not Altitude Related Played Main Roles in Driving Potential Adaptive Evolution at Elevational Range Margin Populations of Taiwan Incense Cedar (Frontiers in genetics · 2020Article
- COFrontiers in plant science · 2020Article
- 275 years of forestry meets genomics inEvolutionary applications · 2020Review
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Authors and funding
12 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the genetic basis of local adaptation is challenging due to the subtle balance among conflicting evolutionary forces that are involved in its establishment and maintenance. One system with which to tease apart these difficulties is clines in adaptive characters. Here we analyzed genetic and phenotypic variation in bud set, a highly heritable and adaptive trait, among 18 populations of Norway spruce (Picea abies), arrayed along a latitudinal gradient ranging from 47°N to 68°N. We confirmed that variation in bud set is strongly clinal, using a subset of five populations. Genotypes for 137 single-nucleotide polymorphisms (SNPs) chosen from 18 candidate genes putatively affecting bud set and 308 control SNPs chosen from 264 random genes were analyzed for patterns of genetic structure and correlation to environment. Population genetic structure was low (F(ST) = 0.05), but latitudinal patterns were apparent among Scandinavian populations. Hence, part of the observed clinal variation should be attributable to population demography. Conditional on patterns of genetic structure, there was enrichment of SNPs within candidate genes for correlations with latitude. Twenty-nine SNPs were also outliers with respect to F(ST). The enrichment for clinal variation at SNPs within candidate genes (i.e., SNPs in PaGI, PaPhyP, PaPhyN, PaPRR7, and PaFTL2) indicated that local selection in the 18 populations, and/or selection in the ancestral populations from which they were recently derived, shaped the observed cline. Validation of these genes using expression studies also revealed that PaFTL2 expression is significantly associated with latitude, thereby confirming the central role played by this gene in the control of phenology in plants.
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