Evidence map›Paper›PMID 22542812›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Clinical decision support with automated text processing for cervical cancer screening.

Kavishwar B Wagholikar, Kathy L MacLaughlin, Michael R Henry, Robert A Greenes, Ronald A Hankey, Hongfang Liu, Rajeev Chaudhry

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.

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  11. Combining text mining with clinical decision support in clinical practice: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kavishwar B WagholikarDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota 55905, USA. waghsk@gmail.com
Kathy L MacLaughlin
Michael R Henry
Robert A Greenes
Ronald A Hankey
Hongfang Liu
Rajeev Chaudhry
Mayo Clinic · USMayo Clinic in Florida · USMayo Clinic in Arizona · US

Funding

Natural language processing for clinical and translational researchR01GM102282 · NIGMS · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG, PAKHOMOV, SERGUEI VS · 2013 to 2016
$2.5M
NIGMS NIH HHS R01 GM102282
6 · The paper itself

Abstract

objectiveTo develop a computerized clinical decision support system (CDSS) for cervical cancer screening that can interpret free-text Papanicolaou (Pap) reports. MATERIALS AND

methodsThe CDSS was constituted by two rulebases: the free-text rulebase for interpreting Pap reports and a guideline rulebase. The free-text rulebase was developed by analyzing a corpus of 49 293 Pap reports. The guideline rulebase was constructed using national cervical cancer screening guidelines. The CDSS accesses the electronic medical record (EMR) system to generate patient-specific recommendations. For evaluation, the screening recommendations made by the CDSS for 74 patients were reviewed by a physician. RESULTS AND DISCUSSION: Evaluation revealed that the CDSS outputs the optimal screening recommendations for 73 out of 74 test patients and it identified two cases for gynecology referral that were missed by the physician. The CDSS aided the physician to amend recommendations in six cases. The failure case was because human papillomavirus (HPV) testing was sometimes performed separately from the Pap test and these results were reported by a laboratory system that was not queried by the CDSS. Subsequently, the CDSS was upgraded to look up the HPV results missed earlier and it generated the optimal recommendations for all 74 test cases. LIMITATIONS: Single institution and single expert study.

conclusionAn accurate CDSS system could be constructed for cervical cancer screening given the standardized reporting of Pap tests and the availability of explicit guidelines. Overall, the study demonstrates that free text in the EMR can be effectively utilized through natural language processing to develop clinical decision support tools.

Indexed as

Decision Support Systems, ClinicalElectronic Health RecordsMass ScreeningNatural Language ProcessingPapanicolaou TestVaginal SmearsAgedData MiningFemaleHumansSensitivity and SpecificityUterine Cervical Neoplasms

Identifiers

PMID22542812
PMCPMC3422840
OpenAlexW2166283755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.