ReviewSeminars in oncology nursing2012
Biomarkers: symptoms, survivorship, and quality of life.
Review in Seminars in oncology nursing, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Symptom clusters experienced by breast cancer patients at various treatment stages: A systematic review.Cancer medicine · 2021Pooled it
- Systematic review of genetic polymorphisms associated with psychoneurological symptoms in breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- Recommendations for high-priority research on cancer-related fatigue in children and adults.Journal of the National Cancer Institute · 2013Guideline
- Cytokine biomarkers and their relationship to symptoms and quality of life in people with HIV-associated Kaposi sarcoma.HIV medicine · 2025Trial
- Serum neurofilament light chain (sNFL) as a predictive biomarker for Chemotherapy-induced peripheral neurotoxicity (CIPN): consideration of current evidence, validation steps, and barriers to CIPN biomarker implementation in clinical practice-a narrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Review
- Persistent nausea burden at peak antiemetic therapy in palliative care: an exploratory study.BMC palliative care · 2026Article
- Associations between self-reported symptoms and circulating protein biomarkers: A scoping review protocol.PloS one · 2026Article
- Utilizing complementary therapy to enhance quality of life and reduce stress and fatigue in pediatric cancer patients.World journal of clinical cases · 2025Review
- Research Priorities of the Oncology Nursing Society: 2024-2027.Oncology nursing forum · 2024Article
- Symptom Science: Advocating for Inclusion of Functional Genetic Polymorphisms.Biological research for nursing · 2019Review
- Genetic Variants Associated with Cancer Pain and Response to Opioid Analgesics: Implications for Precision Pain Management.Seminars in oncology nursing · 2019Review
- Are Perceived Stress and Cytokine Genotypes Clinically Feasible as Predictors of Psychoneuroimmune Symptoms in Advanced Cancer?The Permanente journal · 2019Article
- Longitudinal Changes in Symptom Cluster Membership in Inflammatory Bowel Disease.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2018Article
- Symptom Cluster Research With Biomarkers and Genetics Using Latent Class Analysis.Western journal of nursing research · 2017Review
- Symptom clusters in adults with inflammatory bowel disease.Research in nursing & health · 2017Article
- The role of TRAIL in fatigue induced by repeated stress from radiotherapy.Journal of psychiatric research · 2017Article
- Phenotypic and molecular characteristics associated with various domains of quality of life in oncology patients and their family caregivers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- A murine model of peripheral irradiation-induced fatigue.Behavioural brain research · 2016Article
- Association between single-nucleotide polymorphisms in growth factor genes and quality of life in men with prostate cancer and the general population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Article
- Associations between cytokine genes and a symptom cluster of pain, fatigue, sleep disturbance, and depression in patients prior to breast cancer surgery.Biological research for nursing · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectivesTo review the evidence on a number of biomarkers that show potential clinical utility in the prediction of and treatment responsiveness for the four most common symptoms associated with cancer and its treatment (ie, pain, fatigue, sleep disturbance, depression). DATA SOURCES: Review and synthesis of review articles and data-based publications.
conclusionA growing body of evidence suggests that sensitive and specific biomarkers will be available to assist clinicians with the assessment and management of symptoms. IMPLICATIONS FOR NURSING PRACTICE: Nurses will play a critical role in educating patients about their risk for specific symptoms based on an evaluation of specific biomarkers. Nurses will be involved in using biomarker data to titrate medications based on patient's responses to symptom management interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.