ArticleMalaria journal2012
Differential Plasmodium falciparum infection of Anopheles gambiae s.s. molecular and chromosomal forms in Mali.
Article in Malaria journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Multiple Novel Clades of Anopheline Mosquitoes Caught Outdoors in Northern Zambia.Frontiers in tropical diseases · 2021Article
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- Mosquito microevolution drives Plasmodium falciparum dynamics.Nature microbiology · 2019Article
- Minimal genetic differentiation of the malaria vector Nyssorhynchus darlingi associated with forest cover level in Amazonian Brazil.PloS one · 2019Article
- Mosquitoes (Diptera: Culicidae) and mosquito-borne diseases in Mali, West Africa.Parasites & vectors · 2018Review
- Complete Anopheles funestus mitogenomes reveal an ancient history of mitochondrial lineages and their distribution in southern and central Africa.Scientific reports · 2018Article
- TheeLife · 2017Article
- Malaria vector populations across ecological zones in Guinea Conakry and Mali, West Africa.Malaria journal · 2016Article
- Partitioning the contributions of alternative malaria vector species.Malaria journal · 2016Article
- Genetic Structure of a Local Population of the Anopheles gambiae Complex in Burkina Faso.PloS one · 2016Article
- An Evolution-Based Screen for Genetic Differentiation between Anopheles Sister Taxa Enriches for Detection of Functional Immune Factors.PLoS pathogens · 2015Article
- The kdr-bearing haplotype and susceptibility to Plasmodium falciparum in Anopheles gambiae: genetic correlation and functional testing.Malaria journal · 2015Article
- Dynamics of prevalence and diversity of avian malaria infections in wild Culex pipiens mosquitoes: the effects of Wolbachia, filarial nematodes and insecticide resistance.Parasites & vectors · 2014Article
- Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa.F1000Research · 2014Article
- Molecular characterization, biological forms and sporozoite rate of Anopheles stephensi in southern Iran.Asian Pacific journal of tropical biomedicine · 2014Article
- Equivalent susceptibility of Anopheles gambiae M and S molecular forms and Anopheles arabiensis to Plasmodium falciparum infection in Burkina Faso.Malaria journal · 2013Article
- Article
- Evidence for population-specific positive selection on immune genes of Anopheles gambiae.G3 (Bethesda, Md.) · 2012Article
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8 authors.
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Abstract
backgroundAnopheles gambiae sensu stricto (s.s.) is a primary vector of Plasmodium falciparum in sub-Saharan Africa. Although some physiological differences among molecular and chromosomal forms of this species have been demonstrated, the relative susceptibility to malaria parasite infection among them has not been unequivocally shown. The objective of this study was to investigate P. falciparum circumsporozoite protein infection (CSP) positivity among An. gambiae s.s. chromosomal and molecular forms.
methodsWild An. gambiae from two sites Kela (n=464) and Sidarebougou (n=266) in Mali were screened for the presence of P. falciparum CSP using an enzyme-linked immunosorbent assay (ELISA). Samples were then identified to molecular form using multiple PCR diagnostics (n=713) and chromosomal form using chromosomal karyotyping (n=419).
resultsOf 730 An. gambiae sensu lato (s.l.) mosquitoes, 89 (12.2%) were CSP ELISA positive. The percentage of positive mosquitoes varied by site: 52 (11.2%) in Kela and 37 (13.9%) in Sidarebougou. Eighty-seven of the positive mosquitoes were identified to molecular form and they consisted of nine Anopheles arabiensis (21.4%), 46 S (10.9%), 31 M (12.8%), and one MS hybrid (14.3%). Sixty of the positive mosquitoes were identified to chromosomal form and they consisted of five An. arabiensis (20.0%), 21 Savanna (15.1%), 21 Mopti (30.4%), 11 Bamako (9.2%), and two hybrids (20.0%). DISCUSSION: In this collection, the prevalence of P. falciparum infection in the M form was equivalent to infection in the S form (no molecular form differential infection). There was a significant differential infection by chromosomal form such that, P. falciparum infection was more prevalent in the Mopti chromosomal forms than in the Bamako or Savanna forms; the Mopti form was also the most underrepresented in the collection. Continued research on the differential P. falciparum infection of An. gambiae s.s. chromosomal and molecular forms may suggest that Plasmodium - An. gambiae interactions play a role in malaria transmission.
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