ArticleNorth American journal of medical sciences2011
The relationship between helicobacter pylori infection and gastro-esophageal reflux disease.
Article in North American journal of medical sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Does a relationship still exist between gastroesophageal reflux and Helicobacter pylori in patients with reflux symptoms?World journal of surgical oncology · 2014Trial
- Mid-esophageal mucosal impedance reflects mucosal integrity and phenotypes refractory reflux-like symptoms.BMC gastroenterology · 2026Article
- Genetic Evidence of Association Between Gastroesophageal Reflux Disease and Hypertensive Disorders in Pregnancy.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Evaluation of Salivary Pepsin Levels and Dental Erosion in Patients With Gastroesophageal Reflux Disease.Cureus · 2023Article
- Article
- The association between helicobacter pylori infection and erosive gastroesophageal reflux disease; a cross-sectional study.BMC infectious diseases · 2022Article
- Prevalence of cytotoxin-associated genes ofGastroenterology and hepatology from bed to bench · 2017Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastro-esophageal reflux disease is a common condition, affecting 25%-40% of the population. Increasing attention has been paid to the relationship between Helicobacter pylori infection and reflux esophagitis.
aimThe aim of this study was to investigate the association between CagA+ H. pylori and endoscopically proven gastro-esophageal reflux disease. PATIENTS AND
methodsThe study group included 60 hospital patients with gastro-esophageal reflux disease between 2007 and 2009 as compared with 30 healthy patients from a control group that was age and sex matched. Helicobacter pylori CagA+ was identified by an immunological test (Immunochromatography test) (ACON, USA).
resultsHelicobacter pyloriCagA+ was present in 42/60 (70%) of the patients with gastro-esophageal reflux disease and in 11/30 (36.6%) patients in the control group (p=0.002). The Odds ratio = 0.8004 with 95% Confidence Interval = from 0.3188 to 2.0094. The relative risk=1.35 that indicates an association between Helicobacter pylori and disease.
conclusionsThe presence of Helicobacter pylori is significantly increased in patients with gastro-esophageal reflux disease as compared with the control group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.