Evidence map›Paper›PMID 22539599›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2012

Potential quantitative magnetic resonance imaging biomarkers of coronary remodeling in older hypertensive patients.

Kai Lin, Donald M Lloyd-Jones, Ying Liu, Xiaoming Bi, Debiao Li, James C Carr

Open access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. A clinical strategy to improve the diagnostic performance of 3T non-contrast coronary MRA and noninvasively evaluate coronary distensibility: combination of diastole and systole imaging.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
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  6. The role of latency period in quality management for free-breathing coronary wall MRI.The international journal of cardiovascular imaging · 2015
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  8. The compensation for asynchronous cardiac quiescence in coronary wall MR imaging.The international journal of cardiovascular imaging · 2014
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  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kai LinDepartment of Radiology, Northwestern University, Chicago, IL 60611, USA. kai-lin@northwestern.edu
Donald M Lloyd-Jones
Ying Liu
Xiaoming Bi
Debiao Li
James C Carr
Northwestern Medicine · US

Funding

Chicago Healthy Aging Low Risk MRI Angiography (CHARISMA) StudyR01HL089695 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CARR, JAMES, LLOYD-JONES, DONALD M · 2009 to 2012
$1.8M
NHLBI NIH HHS R01 HL089695NHLBI NIH HHS R01HL089695
6 · The paper itself

Abstract

objectiveTo detect differences in potential magnetic resonance imaging biomarkers of coronary remodeling between older hypertensive patients and healthy controls. METHODS AND

resultsTwo-dimensional black-blood coronary wall magnetic resonance imaging and 3-dimensional whole-heart coronary magnetic resonance angiography were performed on 130 participants (65-84 years), including 65 hypertensive patients and 65 healthy controls. Coronary segments derived from hypertensive participants had a higher mean coronary wall thickness, a smaller vessel area, a smaller coronary wall area, a smaller lumen area, a lower coronary distensibility index, and a higher percent of the coronary wall occupying the vessel area (PWOV) than those from healthy controls. When the average PWOV was set as an ad hoc cutoff point, coronary segments with a high PWOV had a significantly higher mean wall thickness, a higher maximum wall thickness, a smaller vessel area, a smaller lumen area, a lower coronary distensibility index, and a higher coronary plaque index compared with coronary segments with a low PWOV.

conclusionsMagnetic resonance techniques are able to noninvasively detect significant differences in potential imaging biomarkers of coronary remodeling between older hypertensive patients and healthy controls. The PWOV is a promising remodeling feature for quantitatively evaluating the progression of coronary atherosclerosis.

Indexed as

AgedAged, 80 and overBiomarkersCoronary Artery DiseaseCoronary VesselsFemaleHumansHypertensionMagnetic Resonance ImagingMaleBiomarkers

Identifiers

PMID22539599
PMCPMC3558937
OpenAlexW2130704638

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.