ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2012
Supplementation of milled chia seeds increases plasma ALA and EPA in postmenopausal women.
Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02480673 (EFFECT OF Salvia Hispanica L.), which is not on this map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
EFFECT OF Salvia Hispanica L. ( CHIA ) IN THE BIOCHEMICAL METABOLIC SYNDROME COMPONENTS IN PATIENTS IN THE NATIONAL MEDICAL CENTER WEST OF THE MEXICAN SOCIAL SECURITY INSTITUTE
Who cites it
24 citing papers in PubMed, 141 citations in OpenAlex.
- Chia (Salvia hispanica)-supplemented diet ameliorates non-alcoholic fatty liver disease and its metabolic abnormalities in humans.Lipids in health and disease · 2020Trial
- Trial
- A Potential Role of Natural Bioactive Compounds Found in Food in the Prevention of Idiopathic Parkinson's Disease.Nutrients · 2025Review
- Dietary strategies for optimizing omega-3 fatty acid intake: a nutrient database-based evaluation in Taiwan.Frontiers in nutrition · 2025Article
- Exposure Assessment of Essential and Potentially Toxic Elements (PTEs) from Chia Seeds.Journal of xenobiotics · 2024Article
- Chia (Molecules (Basel, Switzerland) · 2023Review
- Chia Oil and Mucilage Nanoemulsion: Potential Strategy to Protect a Functional Ingredient.International journal of molecular sciences · 2023Review
- Long-Chain Polyunsaturated Fatty Acids Effects on Cardiovascular Risk in Childhood: A Narrative Review.Nutrients · 2023Review
- Chia seeds (Food science & nutrition · 2023Review
- Comprehensive Chemical Characterization of Chia (Foods (Basel, Switzerland) · 2022Article
- The Current State of Knowledge onMolecules (Basel, Switzerland) · 2022Review
- Assessment of the Phytochemical and Nutrimental Composition of Dark Chia Seed (Foods (Basel, Switzerland) · 2021Article
- Spectroscopic analysis of chia seeds.Scientific reports · 2021Article
- Article
- Dietary chia (Salvia hispanica L.) improves the nutritional quality of broiler meat.Asian-Australasian journal of animal sciences · 2020Article
- The Chemical Composition and Nutritional Value of Chia Seeds-Current State of Knowledge.Nutrients · 2019Review
- Chia (Gels (Basel, Switzerland) · 2019Article
- Safety of chia seeds (EFSA journal. European Food Safety Authority · 2019Article
- A Comprehensive Review of Chemistry, Sources and Bioavailability of Omega-3 Fatty Acids.Nutrients · 2018Review
- Chia Seed Does Not Improve Cognitive Impairment in SAMP8 Mice Fed with High Fat Diet.Nutrients · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ten postmenopausal women (age 55.6 ± 0.8 years, BMI 24.6 ± 1.1 kg/m²) ingested 25 g/day milled chia seed during a 7-week period, with six plasma samples collected for measurement of α-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA). Subjects operated as their own controls with overnight fasted blood samples taken at baseline (average of two samples), and then after 1, 2, 3, 5, and 7 weeks supplementation. Plasma ALA increased significantly after one week supplementation and was 138 % above baseline levels by the end of the study (overall time effect, P < 0.001). EPA increased 30 % above baseline (overall time effect, P = 0.019) and was correlated across time with ALA (r = 0.84, P = 0.02). No significant change in plasma DPA levels was measured (overall time effect, P = 0.067). Plasma DHA decreased slightly by the end of the study (overall time effect, P = 0.030) and was not correlated with change in ALA. In conclusion, ingestion of 25 g/day milled chia seeds for seven weeks by postmenopausal women resulted in significant increases in plasma ALA and EPA but not DPA and DHA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.