ArticleMolecular brain2012
Barrel cortical neurons and astrocytes coordinately respond to an increased whisker stimulus frequency.
Article in Molecular brain, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 46 citations in OpenAlex.
- Associative memory neurons are recruited in PFC-centered circuits to encode schizophrenia-like behavior by dopaminergic receptor-II.Molecular psychiatry · 2026Article
- The Duality of Astrocyte Neuromodulation: Astrocytes Sense Neuromodulators and Are Neuromodulators.Journal of neurochemistry · 2025Review
- Associative memory cells of encoding fear signals and anxiety are recruited by neuroligin-3-mediated synapse formation.Communications biology · 2024Article
- Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice.Nature communications · 2024Article
- Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance.Nature neuroscience · 2023Article
- Age- and sex-dependent alterations in primary somatosensory cortex neuronal calcium network dynamics during locomotion.Aging cell · 2023Article
- Basolateral Amygdala Astrocytes Are Engaged by the Acquisition and Expression of a Contextual Fear Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Review
- "Tripartite Synapses" in Taste Buds: A Role for Type I Glial-like Taste Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Astrocytes modulate sensory-evoked neuronal network activity.Nature communications · 2020Article
- Intracellular Neuroprotective Mechanisms in Neuron-Glial Networks Mediated by Glial Cell Line-Derived Neurotrophic Factor.Oxidative medicine and cellular longevity · 2019Article
- Searching basic units in memory traces: associative memory cells.F1000Research · 2019Review
- Associative memory cells and their working principle in the brain.F1000Research · 2018Review
- Piriform cortical glutamatergic and GABAergic neurons express coordinated plasticity for whisker-induced odor recall.Oncotarget · 2017Article
- Dual face of axonal inhibitory inputs in the modulation of neuronal excitability in cortical pyramidal neurons.Neural regeneration research · 2017Article
- PKC and CaMK-II inhibitions coordinately rescue ischemia-induced GABAergic neuron dysfunction.Oncotarget · 2017Article
- Synapse Innervation and Associative Memory Cell Are Recruited for Integrative Storage of Whisker and Odor Signals in the Barrel Cortex through miRNA-Mediated Processes.Frontiers in cellular neuroscience · 2017Article
- Associative memory cells: Formation, function and perspective.F1000Research · 2017Review
- Study of the cortical representation of whisker frequency selectivity using voltage-sensitive dye optical imaging.Intravital · 2016Article
- Coordinated Plasticity between Barrel Cortical Glutamatergic and GABAergic Neurons during Associative Memory.Neural plasticity · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNerve cells program the brain codes to manage well-organized cognitions and behaviors. It remains unclear how a population of neurons and astrocytes work coordinately to encode their spatial and temporal activity patterns in response to frequency and intensity signals from sensory inputs.
resultsWith two-photon imaging and electrophysiology to record cellular functions in the barrel cortex in vivo, we analyzed the activity patterns of neurons and astrocytes in response to whisker stimuli with increasing frequency, an environmental stimulus pattern that rodents experience in the accelerated motion. Compared to the resting state, whisker stimulation caused barrel neurons and astrocytes to be activated more synchronously. An increased stimulus frequency up-regulated the activity strength of neurons and astrocytes as well as coordinated their interaction. The coordination among the barrel neurons and astrocytes was fulfilled by increasing their functional connections.
conclusionsOur study reveals that the nerve cells in the barrel cortex encode frequency messages in whisker tactile inputs through setting their activity coordination.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.