ArticleCongestive heart failure (Greenwich, Conn.)
Prognostic value of capnography during rest and exercise in patients with heart failure.
Article in Congestive heart failure (Greenwich, Conn.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Predictive Value of End-Tidal COMedicina (Kaunas, Lithuania) · 2026Observational
- Cardiorespiratory fitness in COPD and HF from the Fitness Registry and the Importance of Exercise: a National Database.European heart journal open · 2025Article
- The Diagnostic Evaluation of the SINEH Cardiopulmonary Triage Scale and the Emergency Severity Index in the Emergency Department: A Comparative Study.Emergency medicine international · 2024Article
- Arterial versus end-tidal carbon dioxide levels in children with congenital heart disease: a prospective cohort study in patients undergoing pulmonary catheterization.Annals of medicine and surgery (2012) · 2023Article
- Technology Applications of Capnography Waveform Analytics for Evaluation of Heart Failure Severity.Journal of cardiovascular translational research · 2020Article
- Inspiratory muscle strength and six-minute walking distance in heart failure: Prognostic utility in a 10 years follow up cohort study.PloS one · 2019Article
- Applications of End-Tidal Carbon Dioxide (ETCO2) Monitoring in Emergency Department; a Narrative Review.Emergency (Tehran, Iran) · 2018Review
- Using the features of the time and volumetric capnogram for classification and prediction.Journal of clinical monitoring and computing · 2017Review
- Clinical usefulness of response profiles to rapidly incremental cardiopulmonary exercise testing.Pulmonary medicine · 2013Article
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Authors and funding
10 authors.
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Abstract
New variables obtained from cardiopulmonary exercise testing (CPX) have received attention in recent years, in particular the partial pressure of end-tidal carbon dioxide (P(ET) CO(2) ). The purpose of this study was to therefore comprehensively assess the ability of resting and exercise P(ET) CO(2) to predict major cardiac events in a heart failure (HF) cohort referred for CPX. A total of 963 patients with systolic HF undergoing symptom-limited CPX were included in the analysis. Resting and exercise P(ET) CO(2) along with other CPX variables were determined, and patients were followed for major adverse events. With regard to resting measures, multivariate analysis revealed that left ventricular ejection fraction was the most robust prognostic marker (P<.001) while resting P(ET) CO(2) added significant predictive value and was retained in the regression (P<.001). When exercise data were considered, the multivariate analysis revealed that the P(ET) CO(2) apex during exercise added predictive value and was retained (P<.05). In what is the largest evaluation of P(ET) CO(2) in the assessment of systolic HF patients to date, the authors substantiate prior (smaller) studies showing prognostic utility of P(ET) CO(2) , both as a resting measure (an important potential screening tool) and during exercise. These data add to the rationale to incorporate P(ET) CO(2) as a routine monitoring component in HF management.
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