ArticlePatient preference and adherence2012
Secondary analysis of electronically monitored medication adherence data for a cohort of hypertensive African-Americans.
Article in Patient preference and adherence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Interventions to increase medication adherence in African-American and Latino populations: a literature review.Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2014Pooled it
- A data-driven typology of asthma medication adherence using cluster analysis.Scientific reports · 2020Trial
- A Systems-Level Approach to Improving Medication Adherence in Hypertensive Latinos: a Randomized Control Trial.Journal of general internal medicine · 2020Trial
- Adherence to home fortification with micronutrient powders in Kenyan pre-school children: self-reporting and sachet counts compared to an electronic monitoring device.BMC public health · 2018Trial
- Medication Routines and Adherence Among Hypertensive African Americans.Journal of clinical hypertension (Greenwich, Conn.) · 2015Trial
- The effect of combining therapeutic drug monitoring of antihypertensive drugs with personalised feedback on adherence and resistant hypertension: the (RHYME-RCT) trial protocol of a multi-centre randomised controlled trial.BMC cardiovascular disorders · 2023Article
- Is Glycemic Control the Secret to Tuberculosis Control?American journal of respiratory and critical care medicine · 2021Article
- A comparison of medication adherence between subsidized and self-paying patients in Malaysia.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2018Article
- Addressing the Social Needs of Hypertensive Patients: The Role of Patient-Provider Communication as a Predictor of Medication Adherence.Circulation. Cardiovascular quality and outcomes · 2017Observational
- Comparison of home fortification with two iron formulations among Kenyan children: Rationale and design of a placebo-controlled non-inferiority trial.Contemporary clinical trials communications · 2017Article
- Predictors of medication nonadherence differ among black and white patients with heart failure.Research in nursing & health · 2015Article
- What puts heart failure patients at risk for poor medication adherence?Patient preference and adherence · 2014Article
- Electronically monitored medication adherence predicts hospitalization in heart failure patients.Patient preference and adherence · 2013Article
- The 'perfect storm' and acute coronary syndrome onset: do psychosocial factors play a role?Progress in cardiovascular diseasesReview
- Adherence to cardiovascular medications: lessons learned and future directions.Progress in cardiovascular diseasesReview
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundElectronic monitoring devices (EMDs) are regarded as the "gold standard" for assessing medication adherence in research. Although EMD data provide rich longitudinal information, they are typically not used to their maximum potential. Instead, EMD data are usually combined into summary measures, which lack sufficient detail for describing complex medication-taking patterns. This paper uses recently developed methods for analyzing EMD data that capitalize more fully on their richness.
methodsRecently developed adaptive statistical modeling methods were used to analyze EMD data collected with medication event monitoring system (MEMS™) caps in a clinical trial testing the effects of motivational interviewing on adherence to antihypertensive medications in a cohort of hypertensive African-Americans followed for 12 months in primary care practices. This was a secondary analysis of EMD data for 141 of the 190 patients from this study for whom MEMS data were available.
resultsNonlinear adherence patterns for 141 patients were generated, clustered into seven adherence types, categorized into acceptable (for example, high or improving) versus unacceptable (for example, low or deteriorating) adherence, and related to adherence self-efficacy and blood pressure. Mean adherence self-efficacy was higher across all time points for patients with acceptable adherence in the intervention group than for other patients. By 12 months, there was a greater drop in mean post-baseline blood pressure for patients in the intervention group, with higher baseline blood pressure values than those in the usual care group.
conclusionAdaptive statistical modeling methods can provide novel insights into patients' medication-taking behavior, which can inform development of innovative approaches for tailored interventions to improve medication adherence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.