ArticleOptics express2012
Statistical connection of binomial photon counting and photon averaging in high dynamic range beam-scanning microscopy.
Article in Optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Versatile software and hardware combo enabling photon counting acquisition and real-time display for multiplexing, 2D and continuous 3D two-photon imaging applications.Neurophotonics · 2022Article
- Video-rate two-photon excited fluorescence lifetime imaging system with interleaved digitization.Optics letters · 2015Article
- High frame-rate multichannel beam-scanning microscopy based on Lissajous trajectories.Optics express · 2014Article
- Exciton coupling model for the emergence of second harmonic generation from assemblies of centrosymmetric molecules.The journal of physical chemistry. A · 2014Article
- Digital deconvolution filter derived from linear discriminant analysis and application for multiphoton fluorescence microscopy.Analytical chemistry · 2014Article
- Synchronous digitization for high dynamic range lock-in amplification in beam-scanning microscopy.The Review of scientific instruments · 2014Article
- Real-time dynamic range and signal to noise enhancement in beam-scanning microscopy by integration of sensor characteristics, data acquisition hardware, and statistical methods.Proceedings of SPIE--the International Society for Optical Engineering · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Data from photomultiplier tubes are typically analyzed using either counting or averaging techniques, which are most accurate in the dim and bright signal limits, respectively. A statistical means of adjoining these two techniques is presented by recovering the Poisson parameter from averaged data and relating it to the statistics of binomial counting from Kissick et al. [Anal. Chem. 82, 10129 (2010)]. The point at which binomial photon counting and averaging have equal signal to noise ratios is derived. Adjoining these two techniques generates signal to noise ratios at 87% to approaching 100% of theoretical maximum across the full dynamic range of the photomultiplier tube used. The technique is demonstrated in a second harmonic generation microscope.
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Registered trials
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