ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2013
Spontaneous osteonecrosis of the knee (SONK).
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 47 citations in OpenAlex.
- A non-invasive, home-based biomechanical therapy for patients with spontaneous osteonecrosis of the knee.Journal of orthopaedic surgery and research · 2016Trial
- Effect of ibandronate on spontaneous osteonecrosis of the knee: a randomized, double-blind, placebo-controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Trial
- A predictive nomogram for treatment response in osteonecrosis patients receiving denosumab with UKA: integrating bone turnover markers and functional parameters.Endocrine connections · 2025Article
- Advantages of cone beam computed tomography for evaluation of subchondral insufficiency fractures of the knee compared to MRI.Scientific reports · 2024Article
- A Current Review in the Orthopedic Management of Osteonecrosis of the knee Secondary to Treatment of Pediatric Hematologic Malignancy.Orthopedic reviews · 2024Article
- The SIFK score: a validated predictive model for arthroplasty progression after subchondral insufficiency fractures of the knee.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Article
- Treatment of spontaneous osteonecrosis of the knee by daily teriparatide: A report of 3 cases.Medicine · 2020Article
- A novel FAM20C mutation causing hypophosphatemic osteomalacia with osteosclerosis (mild Raine syndrome) in an elderly man with spontaneous osteonecrosis of the knee.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Thrombophilia-Associated Factors in Patients with Spontaneous Osteonecrosis of the Knee.Cartilage · 2019Article
- Characteristics, management, and outcomes of spontaneous osteonecrosis of the knee in Indian population.International orthopaedics · 2018Article
- Predictive factors for the progression of spontaneous osteonecrosis of the knee.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Article
- Femoral condyle insufficiency fractures: associated clinical and morphological findings and impact on outcome.Skeletal radiology · 2015Article
- Osteonecrosis of the Knee After Anterior Cruciate Ligament Reconstruction: A Report of 5 Cases.Orthopaedic journal of sports medicine · 2015Article
- MRI of subchondral fractures: a review.Skeletal radiology · 2014Review
- Is the clinical outcome after cartilage treatment affected by subchondral bone edema?Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014Article
- Subchondral osteopenia and accelerated bone remodelling post-ovariectomy - a possible mechanism for subchondral microfractures in the aetiology of spontaneous osteonecrosis of the knee?Journal of anatomy · 2013Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSpontaneous osteonecrosis of the knee (SONK/Morbus Ahlback) mainly affects the medial condyle of elderly women. It is assumed that localized vascular insufficiency leads to necrosis of the subchondral bone with subsequent disruption of the nutrition supply to the cartilage above. The aetiology remains unclear in detail. Operative treatment procedures compete against non-operative strategies, whereas the outcome is unpredictable in many cases.
methodA consecutive case series of five patients suffering from SONK was analysed. All patients underwent a clinical examination, magnetic resonance imaging (MRI) and dual-energy X-ray absorptiometry scan, as well as laboratory analyses and visual analogue scale (VAS) evaluation. Our treatment regime is based on high-dose vitamin D administered orally and intravenous application of 3 mg ibandronate two times within 8 weeks. Another 8 weeks later, all patients were followed up including a follow-up MRI.
resultsWithin 4 weeks, all patients were free of symptoms. The MRI follow-up showed remission of the bone marrow oedema in every case studied. VAS decreased significantly from 7.4 ± 1.0 pre-interventional to 0.8 ± 1.0 post-interventional. No allergic reactions or other side effects were documented.
conclusionWe showed that our treatment regime not only eliminated the pathological findings in the MRI of all cases studied, but also decreased the pain level and functional limitations within a short-time period. LEVEL OF EVIDENCE: IV.
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