Trial reportInternational orthopaedics2012
Pain and activity levels before and after platelet-rich plasma injection treatment of patellar tendinopathy: a prospective cohort study and the influence of previous treatments.
Trial report in International orthopaedics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05579665 (Comparative Effectiveness of Platelet Rich Plasma), which is not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effectiveness of Platelet Rich Plasma (PRP), Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome and Hyaluronic Acid (HA) for the Treatment of Knee Osteoarthritis
Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Platelet-rich plasma in tendon-related disorders: results and indications.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Pooled it
- Platelet-rich plasma: evidence for the treatment of patellar and Achilles tendinopathy--a systematic review.Musculoskeletal surgery · 2015Pooled it
- Clinical applications of platelet-rich plasma in patellar tendinopathy.BioMed research international · 2014Pooled it
- Effect of platelet-rich plasma on the degenerative rotator cuff tendinopathy according to the compositions.Journal of orthopaedic surgery and research · 2019Trial
- Platelet-rich plasma injections for chronic plantar fasciitis.International orthopaedics · 2013Trial
- A Systematic Review of Post-Procedural Rehabilitation Protocols following Percutaneous Needle Tenotomy and Ultrasonic Debridement for Gluteal, Proximal Hamstring, and Patellar Tendinopathy.American journal of physical medicine & rehabilitation · 2026Article
- Lateral Epicondylitis Treated with Platelet-Rich Plasma Injection and Corticosteroid Injection.Journal of orthopaedic case reports · 2024Article
- Role of orthobiologics in managing patellar tendinopathy: A narrative review.Journal of experimental orthopaedics · 2024Review
- Review
- Platelet-rich plasma for jumper's knee: a comprehensive review of efficacy, protocols, and future directions.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Review
- Patellar tendinopathy: an overview of prevalence, risk factors, screening, diagnosis, treatment and prevention.Archives of orthopaedic and trauma surgery · 2023Review
- Review
- Advances in the Clinical Application of Platelet-Rich Plasma in the Foot and Ankle: A Review.Journal of clinical medicine · 2023Review
- Platelet-rich plasma injection in the treatment of patellar tendinopathy: a systematic review and meta-analysis.Knee surgery & related research · 2022Review
- The 2020 NBA Orthobiologics Consensus Statement.Orthopaedic journal of sports medicine · 2021Article
- Platelet-Rich Plasma Applications for Achilles Tendon Repair: A Bridge between Biology and Surgery.International journal of molecular sciences · 2021Review
- Management of Achilles and patellar tendinopathy: what we know, what we can do.Journal of foot and ankle research · 2020Review
- PAST, CURRENT AND FUTURE INTERVENTIONAL ORTHOBIOLOGICS TECHNIQUES AND HOW THEY RELATE TO REGENERATIVE REHABILITATION: A CLINICAL COMMENTARY.International journal of sports physical therapy · 2020Article
- Platelet Concentrates in Musculoskeletal Medicine.International journal of molecular sciences · 2020Review
- Myths and Facts of In-Office Regenerative Procedures for Tendinopathy.American journal of physical medicine & rehabilitation · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to evaluate the outcome of patients with patellar tendinopathy treated with platelet-rich plasma injections (PRP). Additionally, this study examined whether certain characteristics, such as activity level or previous treatment affected the results.
methodsPatients (n = 36) were asked to fill in the Victorian Institute of Sports Assessment - Patellar questionnaire (VISA-P) and visual analogue scales (VAS), assessing pain in activities of daily life (ADL), during work and sports, before and after treatment with PRP. Of these patients, 14 had been treated before with cortisone, ethoxysclerol, and/or surgical treatment (group 1), while the remaining patients had not been treated before (group 2).
resultsOverall, group 1 and group 2 improved significantly on the VAS scales (p < .0.05). However, group 2 also improved on VISA-P (p = .0.003), while group 1 showed less healing potential (p = 0.060). Although the difference between group 1 and group 2 at follow-up was not considered clinically meaningful, over time both groups showed a clinically significant improvement.
conclusionAfter PRP treatment, patients with patellar tendinopathy showed a statistically significant improvement. In addition, these improvements can also be considered clinically meaningful. However, patients who were not treated before with ethoxysclerol, cortisone, and/or surgical treatment showed the improvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.