Evidence map›Paper›PMID 22534870›Full record

ReviewClinical pharmacology and therapeutics2012

Electronic medical records as a tool in clinical pharmacology: opportunities and challenges.

D M Roden, H Xu, J C Denny, R A Wilke

Abstract readReview
In one paragraph

Review in Clinical pharmacology and therapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Integrating pharmacogenomics into the electronic health record by implementing genomic indicators.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  7. Article
  8. Article
  9. A comparative study of different methods for automatic identification of clopidogrel-induced bleedings in electronic health records.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2017
    Article
  10. PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability.Journal of the American Medical Informatics Association : JAMIA · 2016
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Creation and Validation of an EMR-based Algorithm for Identifying Major Adverse Cardiac Events while on Statins.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2014
    Article
  18. Article
  19. Integration of genomics into the electronic health record: mapping terra incognita.Genetics in medicine : official journal of the American College of Medical Genetics · 2013
    Article
  20. Stem cell therapy for chronic heart failure: an updated appraisal.Expert opinion on biological therapy · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

D M RodenDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. dan.roden@vanderbilt.edu
H Xu
J C Denny
R A Wilke

Funding

PHARMACOGENOMICS OF ARRHYTHMIA THERAPYU01HL065962 · NHLBI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2001 to 2009
$24.8M
Pharmacogenomics of Arrhythmia TherapyU19HL065962 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RODEN, DAN M · 2010 to 2014
$17.4M
Vanderbilt Genome-Electronic Records ProjectU01HG004603 · NHGRI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2007 to 2011
$7.3M
Vanderbilt Genome Electronic Records ProjectU01HG006378 · NHGRI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2011 to 2014
$4.0M
NHGRI NIH HHS U01 HG004603NHGRI NIH HHS U01 HG006378NHGRI NIH HHS U01-HG-04603NHLBI NIH HHS U01 HL065962NHLBI NIH HHS U19 HL065962NHLBI NIH HHS U19 HL65962
6 · The paper itself

Abstract

The development and increasing sophistication of electronic medical record (EMR) systems hold the promise of not only improving patient care but also providing unprecedented opportunities for discovery in the fields of basic, translational, and implementation sciences. Clinical pharmacology research in the EMR environment has only recently started to become a reality, with EMRs becoming increasingly populated, methods to mine drug response and other phenotypes becoming more sophisticated, and links being established with DNA repositories.

Indexed as

Electronic Health RecordsGeneticsHumansPharmacogeneticsPharmacology, ClinicalPhenotypeUnited States

Identifiers

PMID22534870
PMCPMC3819803

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.