ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2012
Evolving epidemiologic characteristics of invasive group a streptococcal disease in Utah, 2002-2010.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prognostic factors for streptococcal toxic shock syndrome: systematic review and meta-analysis.BMJ open · 2022Pooled it
- Invasive group A streptococcal disease in pregnant women and young children: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2022Pooled it
- A systematic review of necrotising fasciitis in children from its first description in 1930 to 2018.BMC infectious diseases · 2019Pooled it
- Acute Rheumatic Fever in an Adult Female Patient Presenting With Chest Pain: A Case Report.Cureus · 2025Article
- Toxic Shock Syndrome (TSS) Caused by Group AJournal of Korean medical science · 2024Review
- Strep A: challenges, opportunities, vaccine-based solutions, and economics.NPJ vaccines · 2024Review
- Clinical and molecular epidemiological features of critically ill patients with invasive group A Streptococcus infections: a Belgian multicenter case-series.Annals of intensive care · 2024Article
- Article
- Antibiotic prescribing for adults with group A streptococcal bacteremia in a large healthcare system.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- C10Pred: A First Machine Learning Based Tool to Predict C10 Family Cysteine Peptidases Using Sequence-Derived Features.International journal of molecular sciences · 2022Article
- Clinical and Laboratory Features of Invasive Group A Streptococcal Infections: 8 Years Experience.Turkish archives of pediatrics · 2022Article
- Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease.NPJ vaccines · 2021Article
- Hemorrhagic pneumonia and upper lobe pulmonary cavitary lesion caused byJournal of community hospital internal medicine perspectives · 2021Article
- Disparate Effects of Invasive Group A Streptococcus on Native Americans.Emerging infectious diseases · 2020Article
- Synergistic Activation of Toll-Like and NOD Receptors by Complementary Antigens as Facilitators of Autoimmune Disease: Review, Model and Novel Predictions.International journal of molecular sciences · 2020Review
- Morbidity and mortality in critically ill patients with invasive group A streptococcus infection: an observational study.Critical care (London, England) · 2020Observational
- Systematic analysis of disease-specific immunological signatures in patients with febrile illness from Saudi Arabia.Clinical & translational immunology · 2020Article
- Genomic Surveillance ofFrontiers in microbiology · 2020Article
- Increase in Invasive Group A Streptococcal Disease and Emergence of Mucoid Strains in a Pediatric Population: February-June 2017.Open forum infectious diseases · 2019Article
- Delayed Diagnosis of Acute Rheumatic Fever in a Patient with Multiple Emergency Department Visits.Case reports in pediatrics · 2018Article
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Abstract
backgroundInvasive group A Streptococcus (GAS) infections are associated with substantial morbidity and mortality. Recent national surveillance data report stable rates of invasive GAS disease, although these may not capture geographic variation.
methodsWe performed a population-based, retrospective laboratory surveillance study of invasive GAS disease among Utah residents from 2002-2010. We used Intermountain Healthcare's electronic medical records and data warehouse to identify patients from whom GAS was isolated by culture. We defined clinical syndromes of invasive GAS disease on the basis of International Classification of Diseases, Ninth Revision codes. We abstracted demographic information, comorbidities, and microbiologic and laboratory findings.
resultsFrom 2002-2010, we identified 1514 cases of invasive GAS disease among Utah residents. The estimated mean annual incidence rate was 6.3 cases/100,000 persons, which was higher than the national rate of 3.6 cases/100,000 (P < .01). The incidence of invasive GAS disease in Utah rose from 3.5 cases/100,000 persons in 2002 to 9.8 cases/100,000 persons in 2010 (P = .01). Among children aged <18 years, the incidence of invasive GAS increased from 3.0 cases/100,000 children in 2002 to 14.1 cases/100,000 children in 2010 (P < .01). The increase in the pediatric population was due, in part, to an increase in GAS pneumonia (P = .047). The rate of invasive GAS disease in adults aged 18-64 years increased from 3.4 cases/100 000 persons in 2002 to 7.6 cases/100,000 persons in 2010 (P = .02). Rates among those aged ≥65 years were stable. The incidence of acute rheumatic fever declined from 6.1 to 3.7 cases/100,000 (P = .04).
conclusionsThe epidemiologic characteristics of invasive GAS disease in Utah has changed substantially over the past decade, including a significant increase in the overall incidence of invasive disease-driven primarily by increasing disease in younger persons-that coincided temporally with a decrease in the incidence of acute rheumatic fever.
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