Evidence map›Paper›PMID 22534082›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA

The effectiveness of interventions using electronic reminders to improve adherence to chronic medication: a systematic review of the literature.

Marcia Vervloet, Annemiek J Linn, Julia C M van Weert, Dinny H de Bakker, Marcel L Bouvy, Liset van Dijk

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02454660 (Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages), which is not on this map. Cited by 198 papers, 26 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
198citing papers in PubMed, 26 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02454660 nacompletednot on this map

Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages

TypeinterventionalSponsorUniversity of MichiganRan2015 to 2016Enrolled49ConditionsMedication Non-adherenceArmsSMS (Text messages)
3 · Its place in the literature

Who cites it

198 citing papers in PubMed, 26 syntheses or guidelines pooled it.

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  11. A systematic overview of systematic reviews evaluating medication adherence interventions.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2020
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  13. eHealth interventions for people with chronic kidney disease.The Cochrane database of systematic reviews · 2019
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  14. Family Planning Reminder Systems: An Updated Systematic Review.American journal of preventive medicine · 2018
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138 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcia VervloetNIVEL, Netherlands Institute for Health Services Research, Utrecht, The Netherlands. m.vervloet@nivel.nl
Annemiek J Linn
Julia C M van Weert
Dinny H de Bakker
Marcel L Bouvy
Liset van Dijk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany patients experience difficulties in adhering to long-term treatment. Although patients' reasons for not being adherent are diverse, one of the most commonly reported barriers is forgetfulness. Reminding patients to take their medication may provide a solution. Electronic reminders (automatically sent reminders without personal contact between the healthcare provider and patient) are now increasingly being used in the effort to improve adherence.

objectiveTo examine the effectiveness of interventions using electronic reminders in improving patients' adherence to chronic medication.

methodsA comprehensive literature search was conducted in PubMed, Embase, PsycINFO, CINAHL and Cochrane Central Register of Controlled Trials. Electronic searches were supplemented by manual searching of reference lists and reviews. Two reviewers independently screened all citations. Full text was obtained from selected citations and screened for final inclusion. The methodological quality of studies was assessed.

resultsThirteen studies met the inclusion criteria. Four studies evaluated short message service (SMS) reminders, seven audiovisual reminders from electronic reminder devices (ERD), and two pager messages. Best evidence synthesis revealed evidence for the effectiveness of electronic reminders, provided by eight (four high, four low quality) studies showing significant effects on patients' adherence, seven of which measured short-term effects (follow-up period <6 months). Improved adherence was found in all but one study using SMS reminders, four studies using ERD and one pager intervention. In addition, one high quality study using an ERD found subgroup effects.

conclusionThis review provides evidence for the short-term effectiveness of electronic reminders, especially SMS reminders. However, long-term effects remain unclear.

Indexed as

Medication AdherenceReminder SystemsText MessagingAudiovisual AidsAutomationCell PhoneHumansTelemedicine

Identifiers

PMID22534082
PMCPMC3422829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.