Trial reportBMC geriatrics2012
Proactive and integrated primary care for frail older people: design and methodological challenges of the Utrecht primary care PROactive frailty intervention trial (U-PROFIT).
Trial report in BMC geriatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis.Health technology assessment (Winchester, England) · 2024Pooled it
- Trial
- Examining South Tyrol's Experience: Digital Health Adoption and Workforce Issues in Implementing Italy's Primary Care Reform Under Ministerial Decree No. 77/2022.Epidemiologia (Basel, Switzerland) · 2024Review
- Potential Factors Influencing Adoption of a Primary Care Pathway to Prevent Functional Decline in Older Adults.Canadian geriatrics journal : CGJ · 2023Article
- Case management for integrated care of older people with frailty in community settings.The Cochrane database of systematic reviews · 2023Review
- Factors associated with health-related quality of life among home-dwelling older adults aged 75 or older in Switzerland: a cross-sectional study.Health and quality of life outcomes · 2022Article
- Impact of organizational context on patient outcomes in a proactive primary care program:a longitudinal observational study.BMC geriatrics · 2021Observational
- The INSPIRE Population Survey: development, dissemination and respondent characteristics.BMC medical research methodology · 2021Article
- Multicomponent Intervention and Long-Term Disability in Older Adults: A Nonrandomized Prospective Study.Journal of the American Geriatrics Society · 2021Observational
- Measuring daily functioning in older persons using a frailty index: a cohort study based on routine primary care data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020Article
- Addressing safety risks in integrated care programs for older people living at home: a scoping review.BMC geriatrics · 2020Article
- Supplementation of Mussel Peptides Reduces aging Phenotype, Lipid Deposition and Oxidative Stress in D-Galactose-Induce Aging Mice.The journal of nutrition, health & aging · 2017Article
- Disability in the Individual ADL, IADL, and Mobility among Older Adults: A Prospective Cohort Study.The journal of nutrition, health & aging · 2017Article
- Article
- Can the Medical-nursing Combined Care Promote the Accessibility of Health Services for the Elderly in Nursing Home? A Study Protocol of Analysis of the Effectiveness Regarding Health Service Utilization, Health Status and Satisfaction with Care.The West Indian medical journal · 2015Article
- Validity and reliability of the Katz-15 scale to measure unfavorable health outcomes in community-dwelling older people.The journal of nutrition, health & aging · 2014Article
- Identifying frailty: do the Frailty Index and Groningen Frailty Indicator cover different clinical perspectives? a cross-sectional study.BMC family practice · 2013Article
- Factors associated with geriatric syndromes in older homeless adults.Journal of health care for the poor and underserved · 2013Article
- Using Design Thinking for Co-Creating an Integrated Care Pathway Including Hospital at Home for Older Adults with an Acute Moderate-Severe Respiratory Infection in the Netherlands.International journal of integrated careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrently, primary care for frail older people is reactive, time consuming and does not meet patients' needs. A transition is needed towards proactive and integrated care, so that daily functioning and a good quality of life can be preserved. To work towards these goals, two interventions were developed to enhance the care of frail older patients in general practice: a screening and monitoring intervention using routine healthcare data (U-PRIM) and a nurse-led multidisciplinary intervention program (U-CARE). The U-PROFIT trial was designed to evaluate the effectiveness of these interventions. The aim of this paper is to describe the U-PROFIT trial design and to discuss methodological issues and challenges. METHODS/
designThe effectiveness of U-PRIM and U-CARE is being tested in a three-armed, cluster randomized trial in 58 general practices in the Netherlands, with approximately 5000 elderly individuals expected to participate. The primary outcome is the effect on activities of daily living as measured with the Katz ADL index. Secondary outcomes are quality of life, mortality, nursing home admission, emergency department and out-of-hours General Practice (GP), surgery visits, and caregiver burden. DISCUSSION: In a large, pragmatic trial conducted in daily clinical practice with frail older patients, several challenges and methodological issues will occur. Recruitment and retention of patients and feasibility of the interventions are important issues. To enable broad generalizability of results, careful choices of the design and outcome measures are required. Taking this into account, the U-PROFIT trial aims to provide robust evidence for a structured and integrated approach to provide care for frail older people in primary care.
trial registrationNTR2288.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.