Trial reportJournal of clinical hypertension (Greenwich, Conn.)2012
Reducing clinical inertia in hypertension treatment: a pragmatic randomized controlled trial.
Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01145391 (Health Promotion Outreach To Overcome Clinical Inertia In The Treatment Of Patients With Poorly-Controlled Hypertension), which is not on this map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Health Promotion Outreach To Overcome Clinical Inertia In The Treatment Of Patients With Poorly-Controlled Hypertension
Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Interventions to improve adherence to clinical practice guidelines when treating cardiovascular disease: a systematic review.Irish journal of medical science · 2025Pooled it
- Interventions and contextual factors to improve retention in care for patients with hypertension in primary care: Hermeneutic systematic review.Preventive medicine · 2024Pooled it
- How Behavior Change Strategies are Used to Design Digital Interventions to Improve Medication Adherence and Blood Pressure Among Patients With Hypertension: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Clinical inertia in the pharmacological management of hypertension: A systematic review and meta-analysis.Medicine · 2018Pooled it
- Antihypertensive Medication Regimens Used in the Systolic Blood Pressure Intervention Trial.Hypertension (Dallas, Tex. : 1979) · 2023Trial
- The Retail Outlet Health Kiosk Hypertension Trial (ROKHYT): Pilot Results.American journal of hypertension · 2022Trial
- Analysis of Therapeutic Inertia and Race and Ethnicity in the Systolic Blood Pressure Intervention Trial: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2022Trial
- Multilevel Interventions Demonstrate Mixed Effectiveness for Improving Blood Pressure Outcomes: A Rapid Review.Healthcare (Basel, Switzerland) · 2025Review
- Therapeutic inertia and contributing factors among ambulatory patients with hypertension.BMC cardiovascular disorders · 2024Observational
- A Cross-Sectional Survey of Fixed-Dose Combination Antihypertensive Medicine Prescribing in Twenty-Four Countries, Including Qualitative Insights.Global heart · 2024Article
- Reducing ethnic and racial disparities by improving undertreatment, control, and engagement in blood pressure management with health information technology (REDUCE-BP) hybrid effectiveness-implementation pragmatic trial: Rationale and design.American heart journal · 2023Article
- Association of Elevated Blood Pressure in the Emergency Department With Chronically Elevated Blood Pressure.Journal of the American Heart Association · 2020Article
- Opportunities for improving use of evidence-based therapy in patients with type 2 diabetes and cardiovascular disease.Clinical cardiology · 2019Review
- Development and Preliminary Feasibility of an Automated Hypertension Self-Management System.The American journal of medicine · 2018Article
- Understanding how primary care practitioners perceive an online intervention for the management of hypertension.BMC medical informatics and decision making · 2017Article
- A substudy evaluating treatment intensification on medication adherence among hypertensive patients receiving home blood pressure telemonitoring and pharmacist management.Journal of clinical pharmacy and therapeutics · 2016Article
- Diagnosis and treatment of incident hypertension among patients with diabetes: a U.S. multi-disciplinary group practice observational study.Journal of general internal medicine · 2015Observational
- Is there an association between disease ignorance and self-rated health? The HUNT Study, a cross-sectional survey.BMJ open · 2014Observational
- Antihypertensive medication initiation among young adults with regular primary care use.Journal of general internal medicine · 2014Article
- Interventions to reduce clinical inertia in cardiac risk factor management in renal transplant recipients.Journal of clinical hypertension (Greenwich, Conn.) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Clinical inertia is a major contributor to poor blood pressure (BP) control. The authors tested the effectiveness of an intervention targeting physician, patient, and office system factors with regard to outcomes of clinical inertia and BP control. A total of 591 adult primary care patients with elevated BP (mean systolic BP ≥ 140 mm Hg or mean diastolic BP ≥ 90 mm Hg) were randomized to intervention or usual care. An outreach coordinator raised patient and provider awareness of unmet BP goals, arranged BP-focused primary care clinic visits, and furnished providers with treatment decision support. The intervention reduced clinical inertia (-29% vs -11%, P=.001). Nonetheless, change in BP did not differ between intervention and usual care (-10.1/-4.1 mm Hg vs -9.1/-4.5 mm Hg, P=.50 and 0.71 for systolic and diastolic BP, respectively). Future primary care-focused interventions might benefit from the use of specific medication titration protocols, treatment adherence support, and more sustained patient follow-up visits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.