Evidence map›Paper›PMID 22532849›Full record

Trial reportPloS one2012

Telephone cognitive-behavioral therapy for subthreshold depression and presenteeism in workplace: a randomized controlled trial.

Toshi A Furukawa, Masaru Horikoshi, Norito Kawakami, Masayo Kadota, Megumi Sasaki, Yuki Sekiya, Hiroki Hosogoshi, Masami Kashimura, Kenichi Asano, Hitomi Terashima and 4 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00885014 (Telephone Cognitive-behavioral Therapy for Subthreshold Depression and Presenteeism in Workplace), which is not on this map. Cited by 35 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 7 pooled it
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00885014 phase2 / phase3completednot on this map

Telephone Cognitive-behavioral Therapy for Subthreshold Depression and Presenteeism in Workplace: a Randomized Controlled Trial

TypeinterventionalSponsorKyoto UniversityRan2009 to 2011Enrolled118ConditionsDepressionArmsCBT, EAP
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 7 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
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  3. Interventions to improve return to work in depressed people.The Cochrane database of systematic reviews · 2020
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  7. Psychotherapy for subclinical depression: meta-analysis.The British journal of psychiatry : the journal of mental science · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

Toshi A FurukawaDepartment of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. furukawa@kuhp.kyoto-u.ac.jp
Masaru Horikoshi
Norito Kawakami
Masayo Kadota
Megumi Sasaki
Yuki Sekiya
Hiroki Hosogoshi
Masami Kashimura
Kenichi Asano
Hitomi Terashima
Kazunori Iwasa
Minoru Nagasaku
Louis C Grothaus
GENKI Project
University of Tsukuba · JPNagoya City University · JPGroup Health Cooperative · USKyoto Bunkyo University · JPNaruto University of Education · JPNational Center of Neurology and Psychiatry · JPShujitsu University · JPSurugadai University · JPThe University of Tokyo · JPTokyo Seitoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubthreshold depression is highly prevalent in the general population and causes great loss to society especially in the form of reduced productivity while at work (presenteeism). We developed a highly-structured manualized eight-session cognitive-behavioral program with a focus on subthreshold depression in the workplace and to be administered via telephone by trained psychotherapists (tCBT).

methodsWe conducted a parallel-group, non-blinded randomized controlled trial of tCBT in addition to the pre-existing Employee Assistance Program (EAP) versus EAP alone among workers with subthreshold depression at a large manufacturing company in Japan. The primary outcomes were depression severity as measured with Beck Depression Inventory-II (BDI-II) and presenteeism as measured with World Health Organization Health and Work Productivity Questionnaire (HPQ). In the course of the trial the follow-up period was shortened in order to increase acceptability of the study.

resultsThe planned sample size was 108 per arm but the trial was stopped early due to low accrual. Altogether 118 subjects were randomized to tCBT+EAP (n = 58) and to EAP alone (n = 60). The BDI-II scores fell from the mean of 17.3 at baseline to 11.0 in the intervention group and to 15.7 in the control group after 4 months (p<0.001, Effect size = 0.69, 95%CI: 0.32 to 1.05). However, there was no statistically significant decrease in absolute and relative presenteeism (p = 0.44, ES = 0.15, -0.21 to 0.52, and p = 0.50, ES = 0.02, -0.34 to 0.39, respectively).

conclusionRemote CBT, including tCBT, may provide easy access to quality-assured effective psychotherapy for people in the work force who present with subthreshold depression. Further studies are needed to evaluate the effectiveness of this approach in longer terms. The study was funded by Sekisui Chemicals Co. Ltd.

trial registrationClinicalTrials.gov NCT00885014.

Indexed as

AdultCognitive Behavioral TherapyDepressionDepressive DisorderEfficiencyFemaleFollow-Up StudiesHumansJapanMaleMiddle AgedPsychiatric Status Rating ScalesRemote ConsultationSeverity of Illness IndexTelephoneTreatment Outcome

Identifiers

PMID22532849
PMCPMC3330821
OpenAlexW2085446920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.